A Retrospective, Pilot Study of De Novo Antidepressant Medication Initiation in Intensive Care Unit Patients and Post-ICU Depression
Joint Authors
Flynn, Brigid
He, Jianghua
Haines, Daniel
Hild, Johanna
Stun, Lucy
Ballew, Angie
Green, Justin L.
Satterwhite, Lewis
Source
Critical Care Research and Practice
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-13
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Post-ICU Syndromes (PICS) remain a devastating problem for intensive care unit (ICU) survivors.
It is currently unknown if de novo initiation of an antidepressant medication during ICU stay decreases the prevalence of post-ICU depression.
We performed a retrospective, pilot study evaluating patients who had not previously been on an antidepressant medication and who were started on an antidepressant while in the trauma surgical, cardiothoracic, or medical intensive care unit (ICU).
The PHQ-2 depression scale was used to ascertain the presence of depression after ICU discharge and compared this to historical controls.
Of 2,988 patients admitted to the ICU, 69 patients had de novo initiation of an antidepressant medication and 27 patients were alive and available for study inclusion.
We found the prevalence of depression in these patients to be 26%, which is not statistically different than the prevalence of post-ICU depression in historical controls [95% CI (27.6%, 51.6%)].
De novo initiation of an antidepressant medication did not substantially decrease the prevalence of post-ICU depression in this retrospective, pilot study.
American Psychological Association (APA)
Haines, Daniel& Hild, Johanna& He, Jianghua& Stun, Lucy& Ballew, Angie& Green, Justin L.…[et al.]. 2017. A Retrospective, Pilot Study of De Novo Antidepressant Medication Initiation in Intensive Care Unit Patients and Post-ICU Depression. Critical Care Research and Practice،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1139811
Modern Language Association (MLA)
Haines, Daniel…[et al.]. A Retrospective, Pilot Study of De Novo Antidepressant Medication Initiation in Intensive Care Unit Patients and Post-ICU Depression. Critical Care Research and Practice No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1139811
American Medical Association (AMA)
Haines, Daniel& Hild, Johanna& He, Jianghua& Stun, Lucy& Ballew, Angie& Green, Justin L.…[et al.]. A Retrospective, Pilot Study of De Novo Antidepressant Medication Initiation in Intensive Care Unit Patients and Post-ICU Depression. Critical Care Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1139811
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1139811