Vogt–Koyanagi–Harada Syndrome in a Ugandan: Diagnostic and Therapeutic Challenges
Joint Authors
Kaddumukasa, Mark
Bongomin, Felix
Onen, Francis S.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Vogt–Koyanagi–Harada (VKH) syndrome is a multisystemic autoimmune disease of uncertain pathogenesis.
Infectious aetiology has been proposed which is suggested to lead to the loss of melanocytes in the skin, inner ear, meninges, and uvea in those who are genetically predisposed.
Information regarding VKH syndrome is scanty among the African population.
Case Presentation.
We report a 28-year-old HIV-uninfected Ugandan woman who had previously been well and presented with chronic bilateral panuveitis; symmetrical vitiligo patches on the head, trunk, and upper limbs; tinnitus; and poliosis of the scalp hair, eyelashes, and eyebrows.
A flu-like syndrome preceded this.
Several weeks of prednisolone and azathioprine therapy resulted in remarkable improvement of the ocular and inner ear symptoms.
Conclusion.
A high index of suspicion is required in diagnosing VKH syndrome, even in sub-Saharan Africa where the disease is reported to be rare.
Initiation of prompt and appropriate treatment prevents blindness and other complications.
American Psychological Association (APA)
Bongomin, Felix& Onen, Francis S.& Kaddumukasa, Mark. 2019. Vogt–Koyanagi–Harada Syndrome in a Ugandan: Diagnostic and Therapeutic Challenges. Case Reports in Medicine،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1140895
Modern Language Association (MLA)
Bongomin, Felix…[et al.]. Vogt–Koyanagi–Harada Syndrome in a Ugandan: Diagnostic and Therapeutic Challenges. Case Reports in Medicine No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1140895
American Medical Association (AMA)
Bongomin, Felix& Onen, Francis S.& Kaddumukasa, Mark. Vogt–Koyanagi–Harada Syndrome in a Ugandan: Diagnostic and Therapeutic Challenges. Case Reports in Medicine. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1140895
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1140895