Vogt–Koyanagi–Harada Syndrome in a Ugandan: Diagnostic and Therapeutic Challenges

Joint Authors

Kaddumukasa, Mark
Bongomin, Felix
Onen, Francis S.

Source

Case Reports in Medicine

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-09-16

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Medicine

Abstract EN

Background.

Vogt–Koyanagi–Harada (VKH) syndrome is a multisystemic autoimmune disease of uncertain pathogenesis.

Infectious aetiology has been proposed which is suggested to lead to the loss of melanocytes in the skin, inner ear, meninges, and uvea in those who are genetically predisposed.

Information regarding VKH syndrome is scanty among the African population.

Case Presentation.

We report a 28-year-old HIV-uninfected Ugandan woman who had previously been well and presented with chronic bilateral panuveitis; symmetrical vitiligo patches on the head, trunk, and upper limbs; tinnitus; and poliosis of the scalp hair, eyelashes, and eyebrows.

A flu-like syndrome preceded this.

Several weeks of prednisolone and azathioprine therapy resulted in remarkable improvement of the ocular and inner ear symptoms.

Conclusion.

A high index of suspicion is required in diagnosing VKH syndrome, even in sub-Saharan Africa where the disease is reported to be rare.

Initiation of prompt and appropriate treatment prevents blindness and other complications.

American Psychological Association (APA)

Bongomin, Felix& Onen, Francis S.& Kaddumukasa, Mark. 2019. Vogt–Koyanagi–Harada Syndrome in a Ugandan: Diagnostic and Therapeutic Challenges. Case Reports in Medicine،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1140895

Modern Language Association (MLA)

Bongomin, Felix…[et al.]. Vogt–Koyanagi–Harada Syndrome in a Ugandan: Diagnostic and Therapeutic Challenges. Case Reports in Medicine No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1140895

American Medical Association (AMA)

Bongomin, Felix& Onen, Francis S.& Kaddumukasa, Mark. Vogt–Koyanagi–Harada Syndrome in a Ugandan: Diagnostic and Therapeutic Challenges. Case Reports in Medicine. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1140895

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1140895