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Acute Uric Acid Nephropathy following Epileptic Seizures: Case Report and Review
Joint Authors
Patel, Chinmay
Hattab, Yousef
Wilson, Caitlin P.
Ahmed, Naveed
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Acute hyperuricemia most commonly occurs in patients who experience tumor lysis syndrome.
Hyperuricemia along with other electrolyte abnormalities like hyperkalemia, hypocalcemia, and hyperphosphatemia leads to acute kidney injury (AKI) due to acute uric acid nephropathy which is associated with significant morbidity.
High risk patients are thus closely monitored for signs of these laboratory abnormalities.
Extreme exercise, rhabdomyolysis, and seizures are rare causes of acute hyperuricemia.
Serum uric acid level is not routinely monitored as a part of postictal labs.
We report an unusual case of AKI in a young male with recurrent seizures and no associated rhabdomyolysis who was found to have acute uric acid nephropathy.
Timely administration of Rasburicase prevented the need for dialysis in this patient and led to complete renal recovery.
This case illustrates the importance of doing a urine microscopy and checking uric acid level in patients with recurrent seizures who develop unexplainable AKI, as timely management helps improve outcome.
We also briefly review the pathophysiology of seizure related hyperuricemia and acute uric acid nephropathy.
American Psychological Association (APA)
Patel, Chinmay& Wilson, Caitlin P.& Ahmed, Naveed& Hattab, Yousef. 2019. Acute Uric Acid Nephropathy following Epileptic Seizures: Case Report and Review. Case Reports in Nephrology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1141109
Modern Language Association (MLA)
Patel, Chinmay…[et al.]. Acute Uric Acid Nephropathy following Epileptic Seizures: Case Report and Review. Case Reports in Nephrology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1141109
American Medical Association (AMA)
Patel, Chinmay& Wilson, Caitlin P.& Ahmed, Naveed& Hattab, Yousef. Acute Uric Acid Nephropathy following Epileptic Seizures: Case Report and Review. Case Reports in Nephrology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1141109
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141109