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Apheresis Therapy for Steroid-Resistant Idiopathic Nephrotic Syndrome: Report on a Case Series
Joint Authors
Rostaing, Lionel
Naciri Bennani, Hamza
Jouve, Thomas
Noble, Johan
Malvezzi, Paolo
Tetaz, Rachel
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Idiopathic nephrotic syndrome (INS) represents 15%–30% of adulthood glomerulopathies.
Corticosteroids have been the main treatment for decades and are effective in 70% of minimal-change disease patients and ~30% of focal segmental glomerulosclerosis patients.
Multidrug-resistant (steroids, calcineurin-inhibitors, cyclophosphamide, mycophenolate-mofetil, rituximab) idiopathic nephrotic syndrome is a major therapeutic challenge in nephrology.
Apheresis (double-filtration plasmapheresis or semi specific immunoadsorption) could act by eliminating the circulating factor (apolipoproteinA1b, solubleCD40L, suPAR) increasing glomerular permeability seen in INS.
The aim of the study was to report the outcome of three patients with multidrug-resistant INS treated successfully with apheresis.
American Psychological Association (APA)
Naciri Bennani, Hamza& Jouve, Thomas& Noble, Johan& Rostaing, Lionel& Malvezzi, Paolo& Tetaz, Rachel. 2019. Apheresis Therapy for Steroid-Resistant Idiopathic Nephrotic Syndrome: Report on a Case Series. Case Reports in Nephrology،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1141176
Modern Language Association (MLA)
Naciri Bennani, Hamza…[et al.]. Apheresis Therapy for Steroid-Resistant Idiopathic Nephrotic Syndrome: Report on a Case Series. Case Reports in Nephrology No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1141176
American Medical Association (AMA)
Naciri Bennani, Hamza& Jouve, Thomas& Noble, Johan& Rostaing, Lionel& Malvezzi, Paolo& Tetaz, Rachel. Apheresis Therapy for Steroid-Resistant Idiopathic Nephrotic Syndrome: Report on a Case Series. Case Reports in Nephrology. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1141176
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141176