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Chronic Skull Base Erosion from Temporomandibular Joint Disease Causes Generalized Seizure and Profound Lactic Acidosis
Joint Authors
Wyler, David
Mahla, Michael
Romo, Victor
Dobish, Mark A.
Farrell, Christopher J.
Dhami, Hermandeep S.
Choi, Daniel D.
Reed, Travis
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-27
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
This report displays a rare presentation of lactic acidosis in the setting of status epilepticus (SE).
The differential diagnosis of lactic acidosis is broad and typically originates from states of shock; however, this report highlights an alternative and rare etiology, SE, due to chronic skull base erosion from temporomandibular joint (TMJ) disease.
Lactic acidosis is defined by a pH below 7.35 in the setting of lactate values greater than 5 mmol/L.
Two broad classifications of lactic acidosis exist: a type A lactic acidosis which stems from global or localized tissue hypoxia or a type B lactic acidosis which occurs once mitochondrial oxidative capacity is unable to match glucose metabolism.
SE is an example of a type A lactic acidosis in which oxygen delivery is unable to meet increased cellular energy requirements.
This report is consistent with a prior case series that consists of five patients experiencing generalized tonic-clonic (GTC) seizures and lactic acidosis.
These patients presented with a pH range of 6.8-7.41 and lactate range of 3.8-22.4 mmol/L.
Although severe lactic acidosis following GTC has been described, this is the first report in the literature of chronic skull base erosion from TMJ disease causing SE.
American Psychological Association (APA)
Dobish, Mark A.& Wyler, David& Farrell, Christopher J.& Dhami, Hermandeep S.& Romo, Victor& Choi, Daniel D.…[et al.]. 2018. Chronic Skull Base Erosion from Temporomandibular Joint Disease Causes Generalized Seizure and Profound Lactic Acidosis. Case Reports in Critical Care،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1141223
Modern Language Association (MLA)
Dobish, Mark A.…[et al.]. Chronic Skull Base Erosion from Temporomandibular Joint Disease Causes Generalized Seizure and Profound Lactic Acidosis. Case Reports in Critical Care No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1141223
American Medical Association (AMA)
Dobish, Mark A.& Wyler, David& Farrell, Christopher J.& Dhami, Hermandeep S.& Romo, Victor& Choi, Daniel D.…[et al.]. Chronic Skull Base Erosion from Temporomandibular Joint Disease Causes Generalized Seizure and Profound Lactic Acidosis. Case Reports in Critical Care. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1141223
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141223