Compressive Dorsal Myelopathy Secondary to Extramedullary Hematopoiesis in a Thalassemic Patient
Joint Authors
Alexnader, K. J.
Ismail, Ismail Ibrahim
Massoud, Fathi
Al-Hashel, Jasem Youssef
Source
Case Reports in Neurological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Extramedullary hematopoiesis (EMH) is one of the rare causes of spinal cord compression (SCC).
It results from noncancerous proliferation of hematopoietic tissue outside the bone marrow as a compensatory mechanism for ineffective erythropoiesis.
It occurs in the paraspinal area in 11–15% of thalassemic patients in intermediate and severe cases causing a paraspinal compressive mass.
We present a rare case of spinal EMH with thoracic cord compression in a 22-year-old female with beta thalassemia who presented with paraparesis and we provide a review of literature.
Case Report.
A 22-year-old female patient with a known history of beta thalassemia presented with subacute onset of weakness and numbness of both lower limbs with a sensory level at T6.
Magnetic resonance imaging (MRI) of the dorsal spine showed cord compression secondary to paraspinal EMH from T2 to T9 with most prominent compression over T5.
She was managed with blood transfusion and low-dose radiotherapy.
Conclusion.
Although rare, EMH should be suspected in thalassemic patients presenting with paraplegia.
Treatment with blood transfusions is usually effective.
Other options include radiotherapy, surgery, hydroxyurea or a combination of these modalities.
American Psychological Association (APA)
Ismail, Ismail Ibrahim& Massoud, Fathi& Alexnader, K. J.& Al-Hashel, Jasem Youssef. 2019. Compressive Dorsal Myelopathy Secondary to Extramedullary Hematopoiesis in a Thalassemic Patient. Case Reports in Neurological Medicine،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1141332
Modern Language Association (MLA)
Ismail, Ismail Ibrahim…[et al.]. Compressive Dorsal Myelopathy Secondary to Extramedullary Hematopoiesis in a Thalassemic Patient. Case Reports in Neurological Medicine No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1141332
American Medical Association (AMA)
Ismail, Ismail Ibrahim& Massoud, Fathi& Alexnader, K. J.& Al-Hashel, Jasem Youssef. Compressive Dorsal Myelopathy Secondary to Extramedullary Hematopoiesis in a Thalassemic Patient. Case Reports in Neurological Medicine. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1141332
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141332