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The Effect of Prucalopride on Small Bowel Transit Time in Hospitalized Patients Undergoing Capsule Endoscopy
Joint Authors
Alsahafi, Majid
Cramer, Paula
Chatur, Nazira
Donnellan, Fergal
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The inpatient status is a well-known risk factor for incomplete video capsule endoscopy (VCE) examinations due to prolonged transit time.
We aimed to evaluate the effect of prucalopride on small bowel transit time for hospitalized patients undergoing VCE.
Methods.
We included all hospitalized patients who underwent VCE at a tertiary academic center from October 2011 through September 2016.
A single 2 mg dose of prucalopride was given exclusively for all patients who underwent VCE between March 2014 and December 2015.
VCE studies were excluded if the capsule was retained or endoscopically placed, if other prokinetic agents were given, in cases with technical failure, or if patients had prior gastric or small bowel resection.
Results.
442 VCE were identified, of which 68 were performed in hospitalized patients.
54 inpatients were included, of which 29 consecutive patients received prucalopride.
The prucalopride group had a significantly shorter small bowel transit time compared to the control group (92 versus 275.5, p<0.001).
There was a trend for a higher completion rate in the prucalopride group (93.1% versus 76%, p=0.12).
Conclusions.
Our results suggest that the administration of prucalopride prior to VCE is a simple and effective intervention to decrease small bowel transit time.
American Psychological Association (APA)
Alsahafi, Majid& Cramer, Paula& Chatur, Nazira& Donnellan, Fergal. 2017. The Effect of Prucalopride on Small Bowel Transit Time in Hospitalized Patients Undergoing Capsule Endoscopy. Canadian Journal of Gastroenterology and Hepatology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1141364
Modern Language Association (MLA)
Alsahafi, Majid…[et al.]. The Effect of Prucalopride on Small Bowel Transit Time in Hospitalized Patients Undergoing Capsule Endoscopy. Canadian Journal of Gastroenterology and Hepatology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1141364
American Medical Association (AMA)
Alsahafi, Majid& Cramer, Paula& Chatur, Nazira& Donnellan, Fergal. The Effect of Prucalopride on Small Bowel Transit Time in Hospitalized Patients Undergoing Capsule Endoscopy. Canadian Journal of Gastroenterology and Hepatology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1141364
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141364