Prebiotics: A Novel Approach to Treat Hepatocellular Carcinoma
Joint Authors
Sheikh, Nadeem
Fatima, Naz
Akhtar, Tasleem
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-10
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Hepatocellular carcinoma is one of the fatal malignancies and is considered as the third leading cause of death.
Mutations, genetic modifications, dietary aflatoxins, or impairments in the regulation of oncogenic pathways may bring about liver cancer.
An effective barrier against hepatotoxins is offered by gut-liver axis as a change in gut permeability and expanded translocation of lipopolysaccharides triggers the activation of Toll-like receptors which stimulate the process of hepatocarcinogenesis.
Prebiotics, nondigestible oligosaccharides, have a pivotal role to play when it comes to inducing an antitumor effect.
A healthy gut flora balance is imperative to downregulation of inflammatory cytokines and reducing lipopolysaccharides induced endotoxemia, thus inducing the antitumor effect.
American Psychological Association (APA)
Fatima, Naz& Akhtar, Tasleem& Sheikh, Nadeem. 2017. Prebiotics: A Novel Approach to Treat Hepatocellular Carcinoma. Canadian Journal of Gastroenterology and Hepatology،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1141447
Modern Language Association (MLA)
Fatima, Naz…[et al.]. Prebiotics: A Novel Approach to Treat Hepatocellular Carcinoma. Canadian Journal of Gastroenterology and Hepatology No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1141447
American Medical Association (AMA)
Fatima, Naz& Akhtar, Tasleem& Sheikh, Nadeem. Prebiotics: A Novel Approach to Treat Hepatocellular Carcinoma. Canadian Journal of Gastroenterology and Hepatology. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1141447
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141447