Assessment of serum chemerin, omentin-1 and apelin concentration in normal weight, overweight and obese men in al-Hilla city

Abstract EN

The objective of the study is to evaluate the association between different adipokines (chemerin, omentin-1 and apelin) and obesity.

The study consisted of 88 men who were classified in to three groups according to body mass index.

The first group included 30 normal weight men, the second group included 26 overweight men and the third group included 32 obese men.

Blood was taken from all subjects for determination of serum chemerin, omentin-1 and apelin concentration.

The outcomes of current study shows a significant rise in serum chemerin concentration and a significant decrease in serum omentin-1 concentration in obese group as paralleled with normal weight and overweight group.

The results also show insignificant changes in serum apelin concentration among all of studied groups.

The results of linear regression analysis show a significant positive association between serum chemerin concentration and BMI, while there is a significant negative association between serum omentin-1 concentration and BMI and a significant positive association between serum chemerin and triglycerides concentration in obese group.

This study concludes that there is an association between adipokines (chemerin and omentin) and obesity, also measurement of serum chemerin and omentin may be useful for preventing the complications of obesity.