A Case of Pregnancy Complicated with ATIII Deficiency in a Patient Who Developed Severe Venous Thromboembolism in Her Fourth Pregnancy and Had a Favourable Outcome in Her Subsequent Pregnancy with Careful Management of Anticoagulation Therapy including Edoxaban
Joint Authors
Suzuki, Haruka
Yamanoi, Koji
Ogura, Jumpei
Hirayama, Takahiro
Yasumoto, Koji
Inayama, Yoshihide
Sakai, Mie
Ohara, Tsutomu
Suginami, Koh
Source
Case Reports in Obstetrics and Gynecology
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Congenital ATIII deficiency is one of the congenital thrombophilia diseases that can cause severe venous thromboembolism (VTE) in pregnant patients.
A 30-year-old female, 4 gravida and 2 para, came to the emergency department with a complaint of oedema and pain in the left lower leg at 11 weeks of gestation.
An inferior vena cava thrombus and pulmonary embolism were found.
Because VTE was very severe, artificial abortion was performed, and VTE disappeared rapidly.
She maintained oral administration of edoxaban (NOAC) and got pregnant naturally fifty-five weeks later after the abortion.
Anticoagulation therapy was changed from NOAC to ATIII formulation and unfractionated heparin at 5 weeks of gestation.
The course of pregnancy was good, and a healthy female newborn of 2310 g was delivered vaginally at 37 weeks 6 days of gestation.
In puerperium, anticoagulation therapy was changed to warfarin.
Currently one and one-half years had passed after delivery and no major adverse events or thrombosis has occurred.
This case indicates that severe VTE can develop even in multipara pregnancy and that those who take NOAC may be able to continue pregnancy when they get pregnant.
American Psychological Association (APA)
Sakai, Mie& Ogura, Jumpei& Yamanoi, Koji& Hirayama, Takahiro& Ohara, Tsutomu& Suzuki, Haruka…[et al.]. 2019. A Case of Pregnancy Complicated with ATIII Deficiency in a Patient Who Developed Severe Venous Thromboembolism in Her Fourth Pregnancy and Had a Favourable Outcome in Her Subsequent Pregnancy with Careful Management of Anticoagulation Therapy including Edoxaban. Case Reports in Obstetrics and Gynecology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1141538
Modern Language Association (MLA)
Sakai, Mie…[et al.]. A Case of Pregnancy Complicated with ATIII Deficiency in a Patient Who Developed Severe Venous Thromboembolism in Her Fourth Pregnancy and Had a Favourable Outcome in Her Subsequent Pregnancy with Careful Management of Anticoagulation Therapy including Edoxaban. Case Reports in Obstetrics and Gynecology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1141538
American Medical Association (AMA)
Sakai, Mie& Ogura, Jumpei& Yamanoi, Koji& Hirayama, Takahiro& Ohara, Tsutomu& Suzuki, Haruka…[et al.]. A Case of Pregnancy Complicated with ATIII Deficiency in a Patient Who Developed Severe Venous Thromboembolism in Her Fourth Pregnancy and Had a Favourable Outcome in Her Subsequent Pregnancy with Careful Management of Anticoagulation Therapy including Edoxaban. Case Reports in Obstetrics and Gynecology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1141538
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141538