The Role of Adjunctive Therapies in Septic Shock by Gram Negative MDRXDR Infections
Joint Authors
Girardis, M.
Busani, Stefano
Roat, Erika
Serafini, Giulia
Mantovani, Elena
Biagioni, Emanuela
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Patients with septic shock by multidrug resistant microorganisms (MDR) are a specific sepsis population with a high mortality risk.
The exposure to an initial inappropriate empiric antibiotic therapy has been considered responsible for the increased mortality, although other factors such as immune-paralysis seem to play a pivotal role.
Therefore, beyond conventional early antibiotic therapy and fluid resuscitation, this population may benefit from the use of alternative strategies aimed at supporting the immune system.
In this review we present an overview of the relationship between MDR infections and immune response and focus on the rationale and the clinical data available on the possible adjunctive immunotherapies, including blood purification techniques and different pharmacological approaches.
American Psychological Association (APA)
Busani, Stefano& Roat, Erika& Serafini, Giulia& Mantovani, Elena& Biagioni, Emanuela& Girardis, M.. 2017. The Role of Adjunctive Therapies in Septic Shock by Gram Negative MDRXDR Infections. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141548
Modern Language Association (MLA)
Busani, Stefano…[et al.]. The Role of Adjunctive Therapies in Septic Shock by Gram Negative MDRXDR Infections. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1141548
American Medical Association (AMA)
Busani, Stefano& Roat, Erika& Serafini, Giulia& Mantovani, Elena& Biagioni, Emanuela& Girardis, M.. The Role of Adjunctive Therapies in Septic Shock by Gram Negative MDRXDR Infections. Canadian Journal of Infectious Diseases and Medical Microbiology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141548
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141548