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Central Pontine Myelinolysis in Pediatric Diabetic Ketoacidosis
Joint Authors
Kinoshita, Hannah
Grant, Leon
Xoinis, Konstantine
Purohit, Prashant J.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Central pontine myelinolysis (CPM) is rarely reported in pediatric patients with diabetic ketoacidosis (DKA).
We report this case of a 16-year-old female with new onset diabetes presenting with DKA, who received aggressive fluid resuscitation and sodium bicarbonate in the emergency department.
Later she developed altered mental status concerning for cerebral edema and received hyperosmolar therapy with only transient improvement.
Soon she became apneic requiring emergent endotracheal intubation.
MRI brain showed cerebral edema, CPM, and subdural hemorrhage.
She was extubated on day seven and exhibited mild dysmetria, ataxia, unilateral weakness, and neglect.
Upon discharge she was able to ambulate with a walker and speak and eat without difficulty.
Although less common than cerebral edema, CPM should be considered in DKA patients with acute neurologic deterioration.
Fluid and bicarbonate therapy should be individualized, but larger studies would help guide the management.
Although poor outcomes are reported in CPM, favorable outcomes are possible.
American Psychological Association (APA)
Kinoshita, Hannah& Grant, Leon& Xoinis, Konstantine& Purohit, Prashant J.. 2018. Central Pontine Myelinolysis in Pediatric Diabetic Ketoacidosis. Case Reports in Critical Care،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1141577
Modern Language Association (MLA)
Kinoshita, Hannah…[et al.]. Central Pontine Myelinolysis in Pediatric Diabetic Ketoacidosis. Case Reports in Critical Care No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1141577
American Medical Association (AMA)
Kinoshita, Hannah& Grant, Leon& Xoinis, Konstantine& Purohit, Prashant J.. Central Pontine Myelinolysis in Pediatric Diabetic Ketoacidosis. Case Reports in Critical Care. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1141577
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141577