Lethal End of Spectrum of Clots-Thrombotic Storm
Joint Authors
Rana, Muhammad Asim
Mady, Ahmed Fouad
Naser, Kamal
Lashari, Abdullah Ali
Eltreafi, Rehab
Fischer-Orr, Nicola
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Thrombotic storm (TS) is a rare, acute, hypercoagulable state characterized by multiple thromboembolic events affecting at least two different areas of the vascular system/organs over a short period of time.
Typical triggers include inflammation, infections, minor trauma, surgery, pregnancy, and the puerperium.
A single thrombotic event can set off a number of thromboembolic events, often including unusual locations like hepatic, portal, or renal veins, skin (purpura fulminans), adrenal glands, and cerebral sinus venous thrombosis.
Usually, younger female patients are affected; in some patients, there is an association with an autoimmune disorder like lupus erythematosus, and they show evidence of antiphospholipid antibodies or other phenotypic expressions of anticoagulation disorders.
The majority of patients have no previous history of thromboembolism.
As the diagnosis of thrombotic storm relies solely on clinical symptoms with a lack of specific diagnostic tests, this can result in a delay of diagnosis.
The treatment consists of uninterrupted lifelong anticoagulation.
Sometimes immunomodulatory therapies have been used.
The distinction between extensive thrombotic events like Heparin Induced Thrombosis (HIT), Thrombotic Thrombocytopenic Purpura (TTP), Antiphospholipids Syndrome (APS), and TS can sometimes be difficult, and the etiology of TS remains uncertain.
American Psychological Association (APA)
Rana, Muhammad Asim& Mady, Ahmed Fouad& Lashari, Abdullah Ali& Eltreafi, Rehab& Fischer-Orr, Nicola& Naser, Kamal. 2018. Lethal End of Spectrum of Clots-Thrombotic Storm. Case Reports in Critical Care،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1141622
Modern Language Association (MLA)
Rana, Muhammad Asim…[et al.]. Lethal End of Spectrum of Clots-Thrombotic Storm. Case Reports in Critical Care No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1141622
American Medical Association (AMA)
Rana, Muhammad Asim& Mady, Ahmed Fouad& Lashari, Abdullah Ali& Eltreafi, Rehab& Fischer-Orr, Nicola& Naser, Kamal. Lethal End of Spectrum of Clots-Thrombotic Storm. Case Reports in Critical Care. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1141622
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141622