Detection and Molecular Characterization of Human Adenovirus Infections among Hospitalized Children with Acute Diarrhea in Shanghai, China, 2006–2011
Joint Authors
Lu, Lijuan
Zhong, Huaqing
Su, Liyun
Cao, Lingfeng
Xu, Menghua
Dong, Niuniu
Xu, Jin
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background: Human adenovirus (HAdV) is considered a significant enteropathogen associated with sporadic diarrhea in children.
However, limited data are available regarding the epidemiology of HAdV in hospitalized children with viral diarrhea in Shanghai.
The aim of this study was to characterize the epidemiology of HAdVs and describe their association with acute diarrhea in hospitalized children.
Methods: A total of 674 fecal samples were subjected to PCR or RT-PCR to detect RVA, HuCV, HAstV, and HAdV.
Results: HAdV infections were detected in 4.7% (32/674) of specimens, with detection rates of 13.4% (11/82), 4.6% (8/174), 3.2% (4/124), 4.1% (3/74), 2.0% (2/100), and 3.3% (4/120) from 2006 to 2011, respectively.
Comprehensive detection of the four viruses revealed the presence of a high percentage (90.6%) of coinfections among HAdV-positive samples, where HAdV+RVA was the most prevalent coinfection.
Of the 32 HAdV-positive samples, 50.0% (16/32) were classified as HAdV-41, and 18.8% (6/32) were classified as HAdV-3.
Almost 94.0% of children infected with HAdV were less than 24 months of age.
Conclusions: These results clearly indicated diversity across the HAdV genotypes detected in inpatient children with acute diarrhea in Shanghai and suggested that HAdVs play a role in children with acute diarrhea.
American Psychological Association (APA)
Lu, Lijuan& Zhong, Huaqing& Su, Liyun& Cao, Lingfeng& Xu, Menghua& Dong, Niuniu…[et al.]. 2017. Detection and Molecular Characterization of Human Adenovirus Infections among Hospitalized Children with Acute Diarrhea in Shanghai, China, 2006–2011. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141632
Modern Language Association (MLA)
Lu, Lijuan…[et al.]. Detection and Molecular Characterization of Human Adenovirus Infections among Hospitalized Children with Acute Diarrhea in Shanghai, China, 2006–2011. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1141632
American Medical Association (AMA)
Lu, Lijuan& Zhong, Huaqing& Su, Liyun& Cao, Lingfeng& Xu, Menghua& Dong, Niuniu…[et al.]. Detection and Molecular Characterization of Human Adenovirus Infections among Hospitalized Children with Acute Diarrhea in Shanghai, China, 2006–2011. Canadian Journal of Infectious Diseases and Medical Microbiology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141632
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141632