Ultrasonographic Findings of Renal Cell Carcinomas Associated with Xp11.2 TranslocationTFE3 Gene Fusion
Joint Authors
Ma, Xuelei
Ling, Wenwu
Luo, Yan
Chen, Linyan
Wang, Huiyao
Wang, Xiaoling
Chen, Ni
Zeng, Hao
Li, Yongzhong
Cai, Diming
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
This study was to investigate the features of renal carcinomas associated with Xp11.2 translocations/TFE3 gene fusions (Xp11.2-RCC) on conventional ultrasound (US) and contrast-enhanced ultrasound (CEUS).
Methods.
US and CEUS features of twenty-two cases with histopathologically proven Xp11.2-RCC were retrospectively reviewed.
Results.
22 patients (11 males, 11 females) were included in this study, with a mean age of 28.3 ± 20.4 years.
Eight tumors (36.3%, 8/22) were in left kidney, and 14 tumors (63.7%, 14/22) were in right kidney.
All tumors (100%, 22/22) were mixed echogenicity type.
13 tumors (59.1%, 13/22) presented small dotted calcifications.
The boundary of 14 tumors (63.6%, 14/22) was sharp and the other 8 tumors’ (36.4%, 8/22) boundary was blurry.
By CEUS, in early phase, the solid element of all tumors showed obvious enhancement.
In delayed phase, 13 tumors showed hypoenhancement, seven tumors showed isoenhancement, and 2 tumors showed hyperenhancement.
There were irregular nonenhancement areas in all tumors inside.
Conclusions.
By US and CEUS, when children and adolescents were found to have hyperechoic mixed tumor in kidney with sharp margin and calcification, and the tumors showed obvious enhancement and hypoenhancement with irregular nonenhancement areas in the tumor in early phase and delayed phase, respectively, Xp11.2-RCC should be suspected.
American Psychological Association (APA)
Ling, Wenwu& Ma, Xuelei& Luo, Yan& Chen, Linyan& Wang, Huiyao& Wang, Xiaoling…[et al.]. 2017. Ultrasonographic Findings of Renal Cell Carcinomas Associated with Xp11.2 TranslocationTFE3 Gene Fusion. Contrast Media & Molecular Imaging،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1141709
Modern Language Association (MLA)
Ling, Wenwu…[et al.]. Ultrasonographic Findings of Renal Cell Carcinomas Associated with Xp11.2 TranslocationTFE3 Gene Fusion. Contrast Media & Molecular Imaging No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1141709
American Medical Association (AMA)
Ling, Wenwu& Ma, Xuelei& Luo, Yan& Chen, Linyan& Wang, Huiyao& Wang, Xiaoling…[et al.]. Ultrasonographic Findings of Renal Cell Carcinomas Associated with Xp11.2 TranslocationTFE3 Gene Fusion. Contrast Media & Molecular Imaging. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1141709
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141709