Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Regional Nodal Metastasis in Nasopharyngeal Carcinoma: Correlation with Nodal Staging
Joint Authors
Huang, Bingsheng
Kwong, Dora Lai Wan
Khong, Pek-Lan
Chan, Queenie
Lai, Vincent
Whitcher, Brandon
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To determine if the perfusion parameters by dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of regional nodal metastasis are helpful in characterizing nodal status and to understand the relationship with those of primary tumor of nasopharyngeal carcinoma (NPC).
Materials and Methods.
Newly diagnosed patients imaged between August 2010 and January 2014 and who were found to have enlarged retropharyngeal/cervical lymph nodes suggestive of nodal disease were recruited.
DCE-MRI was performed.
Three quantitative parameters, Ktrans, ve, and kep, were calculated for the largest node in each patient.
Kruskal-Wallis test was used to evaluate the difference in the parameters of the selected nodes of different N stages.
Spearman’s correlation was used to evaluate the relationship between the DCE-MRI parameters in nodes and in primary tumors.
Results.
Twenty-six patients (7 females; 25~67 years old) were enrolled.
Ktrans was significantly different among the patients of N stages (N1, n=3; N2, n=17; N3, n=6), P=0.015.
Median values (range) for N1, N2, and N3 were 0.24 min−1 (0.17~0.26 min−1), 0.29 min−1 (0.17~0.46 min−1), and 0.46 min−1 (0.29~0.70 min−1), respectively.
There was no significant correlation between the parameters in nodes and primary tumors.
Conclusion.
DCE-MRI may play a distinct role in characterizing the metastatic cervical lymph nodes of NPC.
American Psychological Association (APA)
Huang, Bingsheng& Kwong, Dora Lai Wan& Lai, Vincent& Chan, Queenie& Whitcher, Brandon& Khong, Pek-Lan. 2017. Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Regional Nodal Metastasis in Nasopharyngeal Carcinoma: Correlation with Nodal Staging. Contrast Media & Molecular Imaging،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141750
Modern Language Association (MLA)
Huang, Bingsheng…[et al.]. Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Regional Nodal Metastasis in Nasopharyngeal Carcinoma: Correlation with Nodal Staging. Contrast Media & Molecular Imaging No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1141750
American Medical Association (AMA)
Huang, Bingsheng& Kwong, Dora Lai Wan& Lai, Vincent& Chan, Queenie& Whitcher, Brandon& Khong, Pek-Lan. Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Regional Nodal Metastasis in Nasopharyngeal Carcinoma: Correlation with Nodal Staging. Contrast Media & Molecular Imaging. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141750
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141750