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Evaluation of Peripheral Zone Prostate Cancer Aggressiveness Using the Ratio of Diffusion Tensor Imaging Measures
Joint Authors
Vural, Metin
Onay, Aslihan
Ertaş, Gökhan
Akpek, Sergin
Acar, Omer
Saglican, Yesim
Coskun, Bilgen
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-26
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Purpose.
To evaluate the aggressiveness of peripheral zone prostate cancer by correlating the Gleason score (GS) with the ratio of the diffusion tensor imaging (DTI) measures.
Materials and Methods.
Forty-two peripheral zone prostate tumors were imaged using DTI.
Regions of interest focusing on the center of tumor foci and noncancerous tissue were used to extract statistical measures of mean diffusivity (MD) and fractional anisotroy (FA).
Measure ratio was calculated by dividing tumor measure by noncancerous tissue measure.
Results.
Strong correlations are observable between GS and MD measures while weak correlations are present between GS and FA measures.
Minimum tumor MD (MDmin) and the ratio of minimum MD (rMDmin) show the same highest correlation with GS (both ρ=-0.73).
Between GS ≤ 7 (3 + 4) and GS ≥ 7 (4 + 3), differences are significant for all MD measures but for some FA measures.
MD measures perform better than FA measures in discriminating GS ≥ 7 (4 + 3).
Conclusion.
Ratios of MD measures can be used in evaluation of peripheral zone prostate cancer aggressiveness; however tumor MD measures alone perform similarly.
American Psychological Association (APA)
Onay, Aslihan& Ertaş, Gökhan& Vural, Metin& Acar, Omer& Saglican, Yesim& Coskun, Bilgen…[et al.]. 2017. Evaluation of Peripheral Zone Prostate Cancer Aggressiveness Using the Ratio of Diffusion Tensor Imaging Measures. Contrast Media & Molecular Imaging،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1141790
Modern Language Association (MLA)
Onay, Aslihan…[et al.]. Evaluation of Peripheral Zone Prostate Cancer Aggressiveness Using the Ratio of Diffusion Tensor Imaging Measures. Contrast Media & Molecular Imaging No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1141790
American Medical Association (AMA)
Onay, Aslihan& Ertaş, Gökhan& Vural, Metin& Acar, Omer& Saglican, Yesim& Coskun, Bilgen…[et al.]. Evaluation of Peripheral Zone Prostate Cancer Aggressiveness Using the Ratio of Diffusion Tensor Imaging Measures. Contrast Media & Molecular Imaging. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1141790
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141790