Combined Hepatocholangiocarcinoma Associated with Humoral Hypercalcemia of Malignancy and Chronic Inflammatory Demyelinating Polyneuropathy
Joint Authors
Petrozza, Vincenzo
Ciacciarelli, Marco
Bellini, Davide
Polidoro, Alessandro
Clemenzi, Piera
Iuliano, Luigi
Badia, Stefano
Colunga Biancatelli, Ruben Manuel Luciano
Congedo, Viviana
Calvosa, Leonardo
D’Armiento, Eleonora
Misurale, Carmen
Mancini, Massimiliano
Source
Case Reports in Oncological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Paraneoplastic syndromes are often a diagnostic challenge to doctors and may have a heterogeneous presentation, including humoral hypercalcemia of malignancy (HHM), most commonly caused by squamous cell cancer and renal, ovarian, endometrial, and breast cancer.
Chronic inflammatory demyelinating polyneuropathy (CIDP) has been described in patients affected by several types of cancer, especially hematologic malignancies, and a possible paraneoplastic pathogenesis of this neurological disease has been suggested.
This report describes a 56-year-old man with a history of CIDP diagnosed 3 months earlier and persistently elevated aminotransferases for 18 months who was admitted to our internal medicine unit with abdominal pain, fatigue, and severe hypercalcemia with low serum intact parathyroid hormone.
Parathyroid hormone-related protein (PTH-rP) was markedly high.
Liver imaging showed a large hepatic mass in the right lobe, and percutaneous ultrasound-guided biopsy revealed histopathological findings consistent with a combined hepatocholangiocarcinoma (CHCC).
We supposed that both HHM and CIDP could represent a paraneoplastic manifestation of CHCC.
American Psychological Association (APA)
Colunga Biancatelli, Ruben Manuel Luciano& Ciacciarelli, Marco& Polidoro, Alessandro& Clemenzi, Piera& Congedo, Viviana& Calvosa, Leonardo…[et al.]. 2019. Combined Hepatocholangiocarcinoma Associated with Humoral Hypercalcemia of Malignancy and Chronic Inflammatory Demyelinating Polyneuropathy. Case Reports in Oncological Medicine،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1141911
Modern Language Association (MLA)
Colunga Biancatelli, Ruben Manuel Luciano…[et al.]. Combined Hepatocholangiocarcinoma Associated with Humoral Hypercalcemia of Malignancy and Chronic Inflammatory Demyelinating Polyneuropathy. Case Reports in Oncological Medicine No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1141911
American Medical Association (AMA)
Colunga Biancatelli, Ruben Manuel Luciano& Ciacciarelli, Marco& Polidoro, Alessandro& Clemenzi, Piera& Congedo, Viviana& Calvosa, Leonardo…[et al.]. Combined Hepatocholangiocarcinoma Associated with Humoral Hypercalcemia of Malignancy and Chronic Inflammatory Demyelinating Polyneuropathy. Case Reports in Oncological Medicine. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1141911
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141911