![](/images/graphics-bg.png)
Periampullary Metastases from Breast Cancer: A Case Report and Literature Review
Joint Authors
Lin, Yi
Wong, Sio In
Wang, Yuzhou
Lam, Chileong
Peng, Xianghong
Source
Case Reports in Oncological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
We presented a metastatic breast cancer case who was afflicted with obstructive jaundice caused by an ampullary neoplasm.
Since jaundice due to periampullary metastasis from breast cancer was a rare entity, a literature review of similar cases through the PubMed database was done.
A total of 23 additional cases were found.
Among these 24 cases, 5 presented with periampullary metastasis synchronously with the diagnosis of breast cancer, while 19 had metachronous periampullary metastasis with an interval ranging between 1.3 and 23 years from the initial diagnosis of breast cancer to the emergence of jaundice.
It is intriguing to establish a differential diagnosis for common bile tract stricture prior to tissue biopsy, even with diagnostic workups including serum tumor markers, MRI plus MRCP, ERCP with intraductal brushing, and endoscopic ultrasound, in that the clinical, radiological, and endoscopic findings of metastatic lesions overlapped extensively with those found with primary periampullary malignancies.
An immunohistochemical portfolio including cytokeratin7/20 (CK7/20), homeobox protein CDX2, human epidermal growth factor receptor 2 (HER2/neu), estrogen receptor alfa (ERα), progesterone receptor (PgR), mammaglobin, gross cystic disease fluid protein-15 (GCDFP-15), and transacting T-cell-specific transcription factor (GATA-3) was helpful for differential diagnosis among cases with ambiguous microscopic features.
American Psychological Association (APA)
Lin, Yi& Wong, Sio In& Wang, Yuzhou& Lam, Chileong& Peng, Xianghong. 2019. Periampullary Metastases from Breast Cancer: A Case Report and Literature Review. Case Reports in Oncological Medicine،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1141919
Modern Language Association (MLA)
Lin, Yi…[et al.]. Periampullary Metastases from Breast Cancer: A Case Report and Literature Review. Case Reports in Oncological Medicine No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1141919
American Medical Association (AMA)
Lin, Yi& Wong, Sio In& Wang, Yuzhou& Lam, Chileong& Peng, Xianghong. Periampullary Metastases from Breast Cancer: A Case Report and Literature Review. Case Reports in Oncological Medicine. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1141919
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141919