Management of Locally Advanced Esthesioneuroblastoma in a Pregnant Woman
Joint Authors
Guerreiro, Inês Maria
Vieira, Cláudia
Soares, André
Braga, António
Jácome, Manuel
Dinis, José
Source
Case Reports in Oncological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-19
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Esthesioneuroblastoma (ENB) is a rare malignant tumor that commonly develops in the upper nasal cavity.
Standard treatment is not established, especially in locally advanced disease which portends the worse prognosis.
Hereby, we report a case of a 27-year-old, 23-week pregnant woman, with a 2-month history of progressively growing right cervical lymphadenopathy, nasal obstruction, anosmia, frequent episodes of epistaxis, and right frontal headache.
Imagiological evaluation revealed a lesion with 7×5,2×3,2 cm in the nasal fossae with extension to the ethmoidal complex and right olfactive fend and invasion of the endocranial compartment associated with lymphadenopathy.
The biopsy revealed a high-grade EBN.
Neoadjuvant chemotherapy with cisplatin and etoposide was administrated during pregnancy and continued after delivery up to 6 cycles of treatment with partial response.
Radiotherapy followed, with complete response.
This case report is intended to highlight that a high grade of suspicion should be kept in the presence of nonspecific symptoms of nasal obstruction, anosmia, facial pain, and/or headache and focus that chemotherapy is an important component of a combined-treatment modality for locally advanced ENB that can be used during pregnancy in a lifesaving situation.
American Psychological Association (APA)
Guerreiro, Inês Maria& Vieira, Cláudia& Soares, André& Braga, António& Jácome, Manuel& Dinis, José. 2019. Management of Locally Advanced Esthesioneuroblastoma in a Pregnant Woman. Case Reports in Oncological Medicine،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1141927
Modern Language Association (MLA)
Guerreiro, Inês Maria…[et al.]. Management of Locally Advanced Esthesioneuroblastoma in a Pregnant Woman. Case Reports in Oncological Medicine No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1141927
American Medical Association (AMA)
Guerreiro, Inês Maria& Vieira, Cláudia& Soares, André& Braga, António& Jácome, Manuel& Dinis, José. Management of Locally Advanced Esthesioneuroblastoma in a Pregnant Woman. Case Reports in Oncological Medicine. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1141927
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141927