Metastatic Non-Small-Cell Lung Cancer in the Setting of Unilateral Agenesis of the Left Pulmonary Artery: A Case Report and Comprehensive Literature Review
Joint Authors
Agzarian, John
Kadlec, Jakub
Whitehead, Lori
Shargall, Yaron
Source
Case Reports in Oncological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-04-17
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Unilateral absence of the pulmonary artery (UAPA) represents a rare condition that is often associated with cardiac congenital abnormalities but can also be relatively asymptomatic and indolent.
There is a lack of consensus regarding the management of UAPA.
However, in the setting of associated complications and ongoing infection, pulmonary resection is advocated.
Although rare, the association between UAPA and bronchogenic carcinoma has been previously reported in seven published cases.
In the majority of these, anatomic lung resection (most commonly with pneumonectomy) was curative.
We present the first reported case of ipsilateral metastatic non-small-cell lung cancer- (NSCLC-) associated UAPA in a 47-year-old patient with ventilator-dependent hypoxic respiratory failure and bronchorrhea, who had been lost to follow-up for 8 years.
Initial investigations did not yield evidence of malignancy, and confirmation of metastatic disease was made intraoperatively at the time of thoracotomy.
The findings demonstrated evidence of diffuse metastatic pleural disease with lymphangitic carcinomatosis and superimposed infection.
The patient was palliated and passed away shortly thereafter.
In the setting of UAPA, clinicians should have a high index of suspicion for the possibility of malignancy, and if proven, they should consider early resection following appropriate staging.
American Psychological Association (APA)
Agzarian, John& Kadlec, Jakub& Whitehead, Lori& Shargall, Yaron. 2019. Metastatic Non-Small-Cell Lung Cancer in the Setting of Unilateral Agenesis of the Left Pulmonary Artery: A Case Report and Comprehensive Literature Review. Case Reports in Oncological Medicine،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1141972
Modern Language Association (MLA)
Agzarian, John…[et al.]. Metastatic Non-Small-Cell Lung Cancer in the Setting of Unilateral Agenesis of the Left Pulmonary Artery: A Case Report and Comprehensive Literature Review. Case Reports in Oncological Medicine No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1141972
American Medical Association (AMA)
Agzarian, John& Kadlec, Jakub& Whitehead, Lori& Shargall, Yaron. Metastatic Non-Small-Cell Lung Cancer in the Setting of Unilateral Agenesis of the Left Pulmonary Artery: A Case Report and Comprehensive Literature Review. Case Reports in Oncological Medicine. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1141972
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141972