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A Case Presentation of a Patient with Microsatellite Instability and BRAF Mutant Metastatic Colon Cancer and Bibliography Update
Joint Authors
Tzardi, Maria
Thomopoulou, K.
Mavroudis, D.
Souglakos, I.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
This is a case of a patient who presented to the emergency department with acute abdominal pain due to bowel obstruction.
An extended right hemicolectomy with ileosigmoid anastomosis due to an obstructing mass on the splenic flexure was urgently performed.
During operation, liver and peritoneal lesions were detected and samples were also sent for histological analysis.
Pathology report was consistent with poorly differentiated mucinous adenocarcinoma with signet ring cells; peritoneal lesions were confirmed histologically as metastatic.
Genetic testing revealed the BRAFV600E mutation and mismatch repair deficiency (dMMR).
After progressing on 1st line chemotherapy, the patient has a continuing and long-lasting partial response to 2nd line treatment with pembrolizumab.
American Psychological Association (APA)
Thomopoulou, K.& Tzardi, Maria& Mavroudis, D.& Souglakos, I.. 2019. A Case Presentation of a Patient with Microsatellite Instability and BRAF Mutant Metastatic Colon Cancer and Bibliography Update. Case Reports in Oncological Medicine،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1141974
Modern Language Association (MLA)
Thomopoulou, K.…[et al.]. A Case Presentation of a Patient with Microsatellite Instability and BRAF Mutant Metastatic Colon Cancer and Bibliography Update. Case Reports in Oncological Medicine No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1141974
American Medical Association (AMA)
Thomopoulou, K.& Tzardi, Maria& Mavroudis, D.& Souglakos, I.. A Case Presentation of a Patient with Microsatellite Instability and BRAF Mutant Metastatic Colon Cancer and Bibliography Update. Case Reports in Oncological Medicine. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1141974
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1141974