Emerging Risk Profile of Lung Cancer Therapy: Diffuse Alveolar Hemorrhage from Osimertinib
Joint Authors
Forte, Michael J.
Sangani, Rahul G.
Source
Case Reports in Oncological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-30
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Osimertinib is an oral epithelial growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) used primarily in the treatment of metastatic non-small cell lung cancer.
It is usually well tolerated with less than 5% of patients developing significant pulmonary toxicity from the medication, typically within the first few months after initiation.
Previously reported pulmonary adverse reactions include pneumonitis (nonspecific interstitial pneumonia or other forms of acute interstitial process), fleeting asymptomatic infiltrates on imaging, and eosinophilic pneumonia.
We present an interesting case of a 65-year-old female with recurrent metastatic adenocarcinoma of the lung, treated with Osimertinib for 4 months, who developed a previously unreported toxicity of diffuse alveolar hemorrhage (DAH) requiring mechanical ventilatory support.
American Psychological Association (APA)
Forte, Michael J.& Sangani, Rahul G.. 2019. Emerging Risk Profile of Lung Cancer Therapy: Diffuse Alveolar Hemorrhage from Osimertinib. Case Reports in Oncological Medicine،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1142038
Modern Language Association (MLA)
Forte, Michael J.& Sangani, Rahul G.. Emerging Risk Profile of Lung Cancer Therapy: Diffuse Alveolar Hemorrhage from Osimertinib. Case Reports in Oncological Medicine No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1142038
American Medical Association (AMA)
Forte, Michael J.& Sangani, Rahul G.. Emerging Risk Profile of Lung Cancer Therapy: Diffuse Alveolar Hemorrhage from Osimertinib. Case Reports in Oncological Medicine. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1142038
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1142038