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Kalman Filtering for Genetic Regulatory Networks with Missing Values
Joint Authors
Lin, Qiongbin
Liu, Qiuhua
Lai, Tianyue
Wang, Wu
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The filter problem with missing value for genetic regulation networks (GRNs) is addressed, in which the noises exist in both the state dynamics and measurement equations; furthermore, the correlation between process noise and measurement noise is also taken into consideration.
In order to deal with the filter problem, a class of discrete-time GRNs with missing value, noise correlation, and time delays is established.
Then a new observation model is proposed to decrease the adverse effect caused by the missing value and to decouple the correlation between process noise and measurement noise in theory.
Finally, a Kalman filtering is used to estimate the states of GRNs.
Meanwhile, a typical example is provided to verify the effectiveness of the proposed method, and it turns out to be the case that the concentrations of mRNA and protein could be estimated accurately.
American Psychological Association (APA)
Lin, Qiongbin& Liu, Qiuhua& Lai, Tianyue& Wang, Wu. 2017. Kalman Filtering for Genetic Regulatory Networks with Missing Values. Computational and Mathematical Methods in Medicine،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1142319
Modern Language Association (MLA)
Lin, Qiongbin…[et al.]. Kalman Filtering for Genetic Regulatory Networks with Missing Values. Computational and Mathematical Methods in Medicine No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1142319
American Medical Association (AMA)
Lin, Qiongbin& Liu, Qiuhua& Lai, Tianyue& Wang, Wu. Kalman Filtering for Genetic Regulatory Networks with Missing Values. Computational and Mathematical Methods in Medicine. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1142319
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1142319