Bilateral Multiple Focal Choroidal Excavations in a Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH)
Joint Authors
Huang, Ping
Ben Ami, Tal
Li, Weiye
Source
Case Reports in Ophthalmological Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Focal choroidal excavation (FCE) is an unusual configuration characterized by focal thinning and pitting of the choroid in the absence of staphyloma or scleral ectasia.
The etiology and clinical implications of FCE are currently unknown.
We report a case of bilateral multiple FCEs in a patient with a long history of paroxysmal nocturnal hemoglobinuria (PNH).
Focal choriocapillaris thinning and hyperreflectivity of the adjacent outer nuclear layer were revealed by spectral domain optical coherence tomography, which suggests the occlusion of the choriocapillaries and secondary degeneration of the above photoreceptors.
We hypothesize that thrombophilia in the condition of PNH played an important role in the formation of FCE.
Although there is no histopathological evidence to support the association between the choroid changes and PNH, this case may offer new clues as for the etiology of FCE.
American Psychological Association (APA)
Huang, Ping& Ben Ami, Tal& Li, Weiye. 2019. Bilateral Multiple Focal Choroidal Excavations in a Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH). Case Reports in Ophthalmological Medicine،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1142363
Modern Language Association (MLA)
Huang, Ping…[et al.]. Bilateral Multiple Focal Choroidal Excavations in a Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH). Case Reports in Ophthalmological Medicine No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1142363
American Medical Association (AMA)
Huang, Ping& Ben Ami, Tal& Li, Weiye. Bilateral Multiple Focal Choroidal Excavations in a Patient with Paroxysmal Nocturnal Hemoglobinuria (PNH). Case Reports in Ophthalmological Medicine. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1142363
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1142363