Increase of Alkalaine phosphatas in polycythemia vera among Iraq patients

Abstract EN

Ploycythemia is an increase in haemoglobin and red blood cell count which reflecting increase in total red blood cell volume due to an abnormal gene.

this study aimed to ascertain effects of polycythemia on the selected serum alkaline phosphates .

Blood specimens were collected from fourty one polycythemic subjects and thirty subjects with no evidence of polycythemia (control) who are admitted to the Al-kindy hospital in Baghdad city during period from October 2014to feburary 2015with age range (20-70)years.

The results showed that most of patients were females (68.3%) rather than males (31.7%).and also we notice that the majority of patients were at the age between (<20-29) years with (29.3%)and (40-49)years with (22.0%) while it was observed that patients between (50-59) were (12.2%).

Packed cell volum (PCV) which was determind showed increase in packed cell volum with the a highly significant difference (p<0.01) between patients group and control group in comparsion between them.

Our investigation appeared that mean values of serum alkaline phosphates show highlysignificant (P<0.05) inpolycythemic pateints in comparsion with the mean values in the control group .

In conclusion, the current study has been shown the status of the serumalkaline phosphatase influenced by polycythemia.

It is therefore recommended that this parameter with other biochemical parameters such as (uric acid, calcium, cholesterol, creatinine) should be quantitatively measured in all polycythemic subjects and be reversed to normal levels upon the findings of elevated values in order to prevent any subsequent complications.-