Antigiardial activity of garlic (allium sativum)‎ on white mice

Abstract EN

This study aims to determine the effect of cold water, hot water and alcoholic extracts of A.

sativum on intestinal flagellate, G.

lamblia.

The oral administration method is used for one week to evaluate the effect of these plant extracts.

mice are divided to several groups, each group administrates one type of plant extract.

Increasing doses are tested.

Another group administrates a vermifuge drug, metronidazole.

The control group was administrated an equal amount of normal saline.

The oral administrated is achieved twice a day for all mice groups.

The results showed that garlic cold water extract is the best, it exerted significant effects on Giardia lamblia without any side effects.

Total serum bilirubin, total serum protein and plasma fibrinogen were determined as measurements connected with liver functions to investigate liver change due to treatment with the present plant extracts.

Packed cell volume and hemoglobin level also determined.

In these aspects, no significant different is noted in the treated mice compared with control group.-