Adrenocorticotropic Hormone Secreting Pheochromocytoma Underlying Glucocorticoid Induced Pheochromocytoma Crisis
Joint Authors
Geva, Gil A.
Gross, David J.
Atlan, Karine
Ben-Dov, Iddo Z.
Fischer, Matan
Mazeh, Haggi
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-20
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Context.
Pheochromocytomas are hormone secreting tumors of the medulla of the adrenal glands found in 0.1–0.5% of patients with hypertension.
The vast majority of pheochromocytomas secrete catecholamines, but they have been occasionally shown to also secrete interleukins, calcitonin, testosterone, and in rare cases adrenocorticotropic hormone.
Pheochromocytoma crisis is a life threatening event in which high levels of catecholamines cause a systemic reaction leading to organ failure.
Case Description.
A 70-year-old man was admitted with acute myocardial ischemia following glucocorticoid administration as part of an endocrine workup for an adrenal mass.
Cardiac catheterization disclosed patent coronary arteries and he was discharged.
A year later he returned with similar angina-like chest pain.
During hospitalization, he suffered additional events of chest pain, shortness of breath, and palpitations following administration of glucocorticoids as preparation for intravenous contrast administration.
Throughout his admission, the patient demonstrated both signs of Cushing’s syndrome and high catecholamine levels.
Following stabilization of vital parameters and serum electrolytes, the adrenal mass was resected surgically and was found to harbor an adrenocorticotropic hormone secreting pheochromocytoma.
This is the first documented case of adrenocorticotropic hormone secreting pheochromocytoma complicated by glucocorticoid induced pheochromocytoma crisis.
Conclusion.
Care should be taken when administering high doses of glucocorticoids to patients with suspected pheochromocytoma, even in a patient with concomitant Cushing’s syndrome.
American Psychological Association (APA)
Geva, Gil A.& Gross, David J.& Mazeh, Haggi& Atlan, Karine& Ben-Dov, Iddo Z.& Fischer, Matan. 2018. Adrenocorticotropic Hormone Secreting Pheochromocytoma Underlying Glucocorticoid Induced Pheochromocytoma Crisis. Case Reports in Endocrinology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1142946
Modern Language Association (MLA)
Geva, Gil A.…[et al.]. Adrenocorticotropic Hormone Secreting Pheochromocytoma Underlying Glucocorticoid Induced Pheochromocytoma Crisis. Case Reports in Endocrinology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1142946
American Medical Association (AMA)
Geva, Gil A.& Gross, David J.& Mazeh, Haggi& Atlan, Karine& Ben-Dov, Iddo Z.& Fischer, Matan. Adrenocorticotropic Hormone Secreting Pheochromocytoma Underlying Glucocorticoid Induced Pheochromocytoma Crisis. Case Reports in Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1142946
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1142946