Nonfunctioning Pituitary Adenoma That Changed to a Functional Gonadotropinoma
Joint Authors
Ortiz-Plata, Alma
Andino-Ríos, Gerson Geovany
Portocarrero-Ortiz, Lesly
Rojas-Guerrero, Carlos
Terrones-Lozano, Alejandro
Reza-Albarrán, Alfredo Adolfo
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
Pituitary adenomas can be classified as clinically functional or silent.
Depending on the reviewed literature, these are the first or second place in frequency of the total pituitary adenomas.
Even rarer is the presence of a functional gonadotropinoma since only very few case reports exist to date.
The conversion of a clinically silent to functional pituitary adenoma is extraordinarily rare; the mechanisms that explain these phenomena are unknown or not fully understood.
Methods.
We report the case of a woman who initially had a nonfunctional gonadotropinoma and in the course of her medical condition showed biochemical changes in her hormonal pituitary profile compatible with a functional gonadotropinoma.
Results.
We considered that the patient had a functional gonadotropinoma due to the hyperestrogenemia in the context of secondary amenorrhea, resolving the hyperestrogenemia after almost complete resection of the tumor.
Conclusion.
It is necessary to point out from a clinical and/or biochemical point of view the change in functionality that a nonfunctional pituitary adenoma may have.
In the case of our patient, the suspicion of this change in functionality became evident when we found an increase in the FSH/LH ratio and a progressive increase in serum estradiol concentrations when the patient had amenorrhea.
American Psychological Association (APA)
Andino-Ríos, Gerson Geovany& Portocarrero-Ortiz, Lesly& Rojas-Guerrero, Carlos& Terrones-Lozano, Alejandro& Ortiz-Plata, Alma& Reza-Albarrán, Alfredo Adolfo. 2018. Nonfunctioning Pituitary Adenoma That Changed to a Functional Gonadotropinoma. Case Reports in Endocrinology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1142978
Modern Language Association (MLA)
Andino-Ríos, Gerson Geovany…[et al.]. Nonfunctioning Pituitary Adenoma That Changed to a Functional Gonadotropinoma. Case Reports in Endocrinology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1142978
American Medical Association (AMA)
Andino-Ríos, Gerson Geovany& Portocarrero-Ortiz, Lesly& Rojas-Guerrero, Carlos& Terrones-Lozano, Alejandro& Ortiz-Plata, Alma& Reza-Albarrán, Alfredo Adolfo. Nonfunctioning Pituitary Adenoma That Changed to a Functional Gonadotropinoma. Case Reports in Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1142978
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1142978