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Drug-Drug Interaction of Ergotamine with a Combination of Darunavir, Abacavir, and Lamivudine Causing a Fatal Vasospastic Ischemia
Joint Authors
Schoonheydt, Karen
Petit, Elisabeth
Meert, Philippe
Van Laer, Marie
Source
Case Reports in Emergency Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-19
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Ergotamine toxicity has become a rare condition which can be caused by, among others, drug-drug interaction.
In this work we report a case with vasospastic ischemia induced by the wrongful combination of ergotamine with recently started Antiretroviral Therapy.
Clinicians were not aware that patient was self-medicating for years with medication containing ergotamine and caffeine for migraines.
This diagnosis was established after evaluating the evolving ‘and spreading’ ischemia and CT scans and thoroughly interviewing patient’s family.
Treatment was started with intravenous nimodipine and intra-arterial sodium nitroprusside on the affected limbs.
The patient developed severe limb ischemia, cerebral ischemia, and metabolic encephalopathy.
Unfortunately no improvements were noticeable and due to evolving cerebral edema as a result of the ischemia, the patient developed brain herniation and died shortly after.
American Psychological Association (APA)
Petit, Elisabeth& Schoonheydt, Karen& Meert, Philippe& Van Laer, Marie. 2018. Drug-Drug Interaction of Ergotamine with a Combination of Darunavir, Abacavir, and Lamivudine Causing a Fatal Vasospastic Ischemia. Case Reports in Emergency Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1143169
Modern Language Association (MLA)
Petit, Elisabeth…[et al.]. Drug-Drug Interaction of Ergotamine with a Combination of Darunavir, Abacavir, and Lamivudine Causing a Fatal Vasospastic Ischemia. Case Reports in Emergency Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1143169
American Medical Association (AMA)
Petit, Elisabeth& Schoonheydt, Karen& Meert, Philippe& Van Laer, Marie. Drug-Drug Interaction of Ergotamine with a Combination of Darunavir, Abacavir, and Lamivudine Causing a Fatal Vasospastic Ischemia. Case Reports in Emergency Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1143169
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143169