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The Role of Acetyl Cysteine in Cocaethylene (Non-Acetaminophen) Acute Liver Failure
Joint Authors
Kalantari, Hossein
Dhaliwal, Amaninder
Jenninigs, Catherine Ann
Worku Hassen, Getaw
Source
Case Reports in Emergency Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-26
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Acute liver failure can result from acetaminophen overdose, viral infection, toxins, and other disease conditions.
Liver transplant is available in limited fashion and the criteria are strict as to who should get an available liver.
N- Acetyl Cysteine (NAC) has been used in non-acetaminophen induced liver failure with success.
Here we report a case of acute liver failure from cocaethylene that was reversed with NAC along with other medical therapy.
Case Presentation.
A 50-year-old female patient presented to the Emergency Department (ED) with a two-day history of coffee ground vomiting and hematemesis.
She reported occasional substance abuse and heavy alcoholism.
She reported shortness of breath and chest pain from the recurrent forceful vomiting.
The rest of the review of systems was unremarkable except a fall from intoxication.
Physical examination revealed anicteric conjunctiva and nontender abdomen and her vital signs were within normal limits.
Initial blood work revealed acute liver and renal failure.
The patient was started with general medical management and liver transplant service rejected the case due to active substance abuse.
She underwent brief hemodialysis and was started on NAC.
Over the course of her hospital stay her liver function and kidney function improved significantly and patient was discharged to home.
Conclusion.
In cases where liver transplant is not an option for various reasons including active substance abuse, a trial of N-Acetyl Cysteine may be beneficial and should be considered in the Emergency Department.
American Psychological Association (APA)
Worku Hassen, Getaw& Dhaliwal, Amaninder& Jenninigs, Catherine Ann& Kalantari, Hossein. 2018. The Role of Acetyl Cysteine in Cocaethylene (Non-Acetaminophen) Acute Liver Failure. Case Reports in Emergency Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1143185
Modern Language Association (MLA)
Worku Hassen, Getaw…[et al.]. The Role of Acetyl Cysteine in Cocaethylene (Non-Acetaminophen) Acute Liver Failure. Case Reports in Emergency Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1143185
American Medical Association (AMA)
Worku Hassen, Getaw& Dhaliwal, Amaninder& Jenninigs, Catherine Ann& Kalantari, Hossein. The Role of Acetyl Cysteine in Cocaethylene (Non-Acetaminophen) Acute Liver Failure. Case Reports in Emergency Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1143185
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143185