Hemophilia A Complicated by Ulcerative Colitis
Joint Authors
Carlan, S. J.
Madruga, Mario
Olivier, Maxim
Ge, Li
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-04
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Background.
Hemophilia A is an X-linked recessive disorder characterized by defective synthesis of Factor VIII protein.
Depending on the level of FVIII activity, patients may present with easy bruising, inadequate clotting of traumatic or mild injury, or in severe hemophilia, spontaneous hemorrhage.
Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that is reported to have a decreased frequency of occurrence in subjects with coagulation disorders.
Case.
A 26-year-old white male with Hemophilia A was admitted for one month of rectal bleeding.
The bleeding continued despite Factor VIII replacement and colonoscopy and biopsy were performed confirming the presence of active UC.
Conclusion.
Ulcerative colitis with underlying F VIII deficiency can result in serious, prolonged, and possibly fatal bleeding if left unrecognized and untreated.
Treatment of both conditions concurrently utilizing tertiary facilities and consultations appears to be the safest strategy for management.
American Psychological Association (APA)
Olivier, Maxim& Madruga, Mario& Carlan, S. J.& Ge, Li. 2018. Hemophilia A Complicated by Ulcerative Colitis. Case Reports in Gastrointestinal Medicine،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143406
Modern Language Association (MLA)
Olivier, Maxim…[et al.]. Hemophilia A Complicated by Ulcerative Colitis. Case Reports in Gastrointestinal Medicine No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1143406
American Medical Association (AMA)
Olivier, Maxim& Madruga, Mario& Carlan, S. J.& Ge, Li. Hemophilia A Complicated by Ulcerative Colitis. Case Reports in Gastrointestinal Medicine. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143406
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143406