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Coronary Heart Disease and an Incidental Parathyroid Carcinoma
Joint Authors
Stoll, M.
Nebiker, C. A.
Grobholz, R.
Remonda, Luca
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A 71-year-old woman was admitted with angina pectoris.
During hospitalization she developed a myocardial infarction (NSTEMI).
Laboratory results revealed a mild elevated troponin and an elevated calcium level (3.35 mmol/l).
Subsequently, there was a decreased phosphate (0.36 mmol/l [normal 0.81-1.62 mmol/l]) as well as 16-fold elevated serum level of parathyroid hormone (PTH, 1156 ng/l [normal 10-73 ng/l]), indicating a primary hyperparathyroidism.
Sonographically a thyroidal node was detected, not clearly demarcated (TIRADS 5).
FNA showed a monomorphic, partial follicular cell population with an immunohistochemical positivity for PTH.
Magnetic resonance imaging (MRI) showed a 5 cm large tumor at the right caudal pole of the thyroid with compression of the dorsolateral trachea without infiltration.
Surgical removal with en bloc resection of the right hemithyroid with parathyroidectomy was performed.
Postoperatively the PTH level dropped to 12.1 ng/l.
Pathological examination revealed a 5 cm tumor with infiltration of the thyroid and a perineural invasion.
The diagnosis of a presymptomatic parathyroid carcinoma could be established.
The affirmative histopathological diagnosis of a parathyroid carcinoma can be challenging and is limited to tumors with evidence of invasive growth in adjacent structures such as the thyroid and/or soft tissue, perineural spaces, angioinvasion of capsular and/or extracapsular vessels, and/or documented metastases.
American Psychological Association (APA)
Stoll, M.& Nebiker, C. A.& Remonda, Luca& Grobholz, R.. 2019. Coronary Heart Disease and an Incidental Parathyroid Carcinoma. Case Reports in Pathology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1143533
Modern Language Association (MLA)
Stoll, M.…[et al.]. Coronary Heart Disease and an Incidental Parathyroid Carcinoma. Case Reports in Pathology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1143533
American Medical Association (AMA)
Stoll, M.& Nebiker, C. A.& Remonda, Luca& Grobholz, R.. Coronary Heart Disease and an Incidental Parathyroid Carcinoma. Case Reports in Pathology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1143533
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143533