TTF1 Expression in Pulmonary Metastatic Rectal Adenocarcinoma
Joint Authors
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-05
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Thyroid transcription factor (TTF-1) is a tissue-specific nuclear transcription factor expressed developing thyroid, respiratory epithelium, and diencephalon.
TTF-1 is thought to be expressed specifically in most thyroid tumors and in a significant subset of pulmonary neoplasms.
However, recent studies on its expression in extrapulmonary carcinomas have demonstrated that TTF-1 is not as specific for lung and thyroid carcinomas as was previously thought: positivity of this marker can be observed, although much less frequently, in some carcinomas arising in other organs, such as the ovaries, endometrium, colon, and breast, as well as in some tumors of the central nervous system.
Case reports of patients with TTF-1-positive colon adenocarcinoma are present in medical literature, but there are only a few cases of TTF-1-positive rectal adenocarcinoma.
We present the case of a patient with rectal adenocarcinoma with lung metastasis found to be TTF-1-positive on immunohistochemistry.
A review of the available literature is also included.
American Psychological Association (APA)
Aversa, Sara& Bellan, Cristiana. 2018. TTF1 Expression in Pulmonary Metastatic Rectal Adenocarcinoma. Case Reports in Gastrointestinal Medicine،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143547
Modern Language Association (MLA)
Aversa, Sara& Bellan, Cristiana. TTF1 Expression in Pulmonary Metastatic Rectal Adenocarcinoma. Case Reports in Gastrointestinal Medicine No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1143547
American Medical Association (AMA)
Aversa, Sara& Bellan, Cristiana. TTF1 Expression in Pulmonary Metastatic Rectal Adenocarcinoma. Case Reports in Gastrointestinal Medicine. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143547
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143547