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Vigabatrin-Induced Encephalopathy in a 5.5-Month-Old Girl with Infantile Spasms due to Tuberous Sclerosis
Joint Authors
Maritsi, Despoina N.
Vartzelis, George
Klinaki, Eleni
Argyri, Ioanna
Amountza, Georgia
Ioannidou, Gerina
Garoufi, Anastasia
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-25
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
A 5.5-month-old female infant with tuberous sclerosis complex presented with infantile spasms and was treated with vigabatrin.
As her condition did not improve, she was given adrenocorticotropic hormone (ACTH) intramuscularly which stopped the spasms and improved the electroencephalogram (EEG) abnormalities.
However, she developed encephalopathy with apathy, drowsiness, and generalized slowing in the EEG.
Discontinuation of vigabatrin quickly improved her symptoms and reversed the EEG slowing.
A high index of suspicion is required in order to diagnose vigabatrin-induced encephalopathy, especially as the underlying disorders of these patients can be erroneously considered the cause of the observed encephalopathy.
American Psychological Association (APA)
Klinaki, Eleni& Argyri, Ioanna& Amountza, Georgia& Ioannidou, Gerina& Maritsi, Despoina N.& Garoufi, Anastasia…[et al.]. 2019. Vigabatrin-Induced Encephalopathy in a 5.5-Month-Old Girl with Infantile Spasms due to Tuberous Sclerosis. Case Reports in Pediatrics،Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1143746
Modern Language Association (MLA)
Klinaki, Eleni…[et al.]. Vigabatrin-Induced Encephalopathy in a 5.5-Month-Old Girl with Infantile Spasms due to Tuberous Sclerosis. Case Reports in Pediatrics No. 2019 (2019), pp.1-3.
https://search.emarefa.net/detail/BIM-1143746
American Medical Association (AMA)
Klinaki, Eleni& Argyri, Ioanna& Amountza, Georgia& Ioannidou, Gerina& Maritsi, Despoina N.& Garoufi, Anastasia…[et al.]. Vigabatrin-Induced Encephalopathy in a 5.5-Month-Old Girl with Infantile Spasms due to Tuberous Sclerosis. Case Reports in Pediatrics. 2019. Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1143746
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143746