Secondary HLH Case Report Highlighting Clinical Challenges

Joint Authors

El Fakih, Riad
Mohamed, Said Y.
Alnounou, Randa
Elgohary, Ghada

Source

Case Reports in Hematology

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-2, 2 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-03-04

Country of Publication

Egypt

No. of Pages

2

Main Subjects

Diseases

Abstract EN

A 19-year-old patient with relapsed acute myeloid leukemia (AML) developed severe and prolonged cytopenia and unexplained jaundice and fever after salvage chemotherapy.

His workup revealed hemophagocytosis on the bone marrow biopsy.

He was treated for HLH (hemophagocytic lymphohistiocytosis) secondary to AML and chemotherapy.

The patient died on day 56 after starting his salvage chemotherapy.

Unexpectedly, after his death, the microbiology laboratory reported positive mycobacterial growth from a bronchoalveolar lavage (BAL) sample taken during the workup of his fever.

This case illustrates the difficulties in the diagnostic workup of HLH to identify triggers in a timely manner so that a targeted and specific therapy can be administered quickly, given the rapid and deadly evolution of the HLH process.

American Psychological Association (APA)

El Fakih, Riad& Mohamed, Said Y.& Alnounou, Randa& Elgohary, Ghada. 2018. Secondary HLH Case Report Highlighting Clinical Challenges. Case Reports in Hematology،Vol. 2018, no. 2018, pp.1-2.
https://search.emarefa.net/detail/BIM-1143749

Modern Language Association (MLA)

El Fakih, Riad…[et al.]. Secondary HLH Case Report Highlighting Clinical Challenges. Case Reports in Hematology No. 2018 (2018), pp.1-2.
https://search.emarefa.net/detail/BIM-1143749

American Medical Association (AMA)

El Fakih, Riad& Mohamed, Said Y.& Alnounou, Randa& Elgohary, Ghada. Secondary HLH Case Report Highlighting Clinical Challenges. Case Reports in Hematology. 2018. Vol. 2018, no. 2018, pp.1-2.
https://search.emarefa.net/detail/BIM-1143749

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1143749