Coexistent Breast Cancer and Essential Thrombocythemia: How We Addressed the Therapeutic Challenges
Joint Authors
Seegobin, Karan
Gharia, Bharatsinh
Maharaj, Satish
Zuberi, Lara
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-12
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Essential thrombocythemia (ET) occurring with breast cancer is uncommon; the therapeutic approach varies and poses a challenge.
A 65-year-old female presented to us after being diagnosed with hormone positive, HER2-negative infiltrating ductal carcinoma.
She had a platelet count of 600 thou/cu mm.
Her JAK2 mutation was positive.
Bone marrow biopsy showed increased megakaryocytes.
She was diagnosed with ET in the setting of breast cancer.
She underwent breast conservation surgery after which aspirin was resumed.
Anticipating thrombocytopenia during chemotherapy and given the absence of data combining hydroxyurea with standard chemotherapy used for breast cancer, we felt it prudent to delay cytoreductive therapy for her ET until after completion of breast cancer treatment.
Her average platelet count during chemotherapy was 480 thou/cu mm with the lowest being 377 thou/cu mm.
Her platelet count remained at goal between 300 and 350 thou/cu mm after four months of hydroxyurea.
American Psychological Association (APA)
Seegobin, Karan& Gharia, Bharatsinh& Maharaj, Satish& Zuberi, Lara. 2018. Coexistent Breast Cancer and Essential Thrombocythemia: How We Addressed the Therapeutic Challenges. Case Reports in Hematology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1143759
Modern Language Association (MLA)
Seegobin, Karan…[et al.]. Coexistent Breast Cancer and Essential Thrombocythemia: How We Addressed the Therapeutic Challenges. Case Reports in Hematology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1143759
American Medical Association (AMA)
Seegobin, Karan& Gharia, Bharatsinh& Maharaj, Satish& Zuberi, Lara. Coexistent Breast Cancer and Essential Thrombocythemia: How We Addressed the Therapeutic Challenges. Case Reports in Hematology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1143759
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143759