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Seizures following Intoxication with a Common Antituberculosis Drug
Joint Authors
Benlamkaddem, Said
Lahlou, Adnane
Berdai, Mohamed Adnane
Harandou, Mustapha
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-05
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Isoniazid is an antimycobacterial agent commonly prescribed in most tuberculosis chemotherapy regimens.
Its side effects are widely known including mainly liver toxicity and peripheral neuropathy.
The toxic effects of isoniazid are dose-related.
Toxic doses are estimated at 35–40 mg/kg and fatal doses at 150 mg/kg.
Treatment consists primarily of basic life support, antiepileptic drugs, and pyridoxine.
The case is of one of the children with intentional isoniazid poisoning, the drug belonging to an uncle currently under antituberculosis treatment, resulting in tonic-clonic seizures.
During her hospitalization in the paediatric intensive care unit, her neurological status as well as her lab values was closely monitored, and despite initial deterioration, the patient was discharged from critical care a week after full recovery.
American Psychological Association (APA)
Lahlou, Adnane& Benlamkaddem, Said& Berdai, Mohamed Adnane& Harandou, Mustapha. 2019. Seizures following Intoxication with a Common Antituberculosis Drug. Case Reports in Pediatrics،Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1143789
Modern Language Association (MLA)
Lahlou, Adnane…[et al.]. Seizures following Intoxication with a Common Antituberculosis Drug. Case Reports in Pediatrics No. 2019 (2019), pp.1-3.
https://search.emarefa.net/detail/BIM-1143789
American Medical Association (AMA)
Lahlou, Adnane& Benlamkaddem, Said& Berdai, Mohamed Adnane& Harandou, Mustapha. Seizures following Intoxication with a Common Antituberculosis Drug. Case Reports in Pediatrics. 2019. Vol. 2019, no. 2019, pp.1-3.
https://search.emarefa.net/detail/BIM-1143789
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143789