Acquired Amegakaryocytic Thrombocytopenia and Pure Red Cell Aplasia in Thymoma
Joint Authors
Sharma, Eliza
Shrestha, Binav
Dahal, Sumit
Dahal, Suyash
Bhattarai, Bikash
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-11
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Association of thymoma with myasthenia gravis, pure red cell aplasia, and aplastic anemia is well documented.
However, thymoma complicated by acquired amegakaryocytic thrombocytopenia (AAMT) is rarely reported.
Here, we present a case of a 60-year-old male with past medical history of recurrent invasive thymoma who presented with cough and blood in sputum.
He was found to have severe normocytic normochromic anemia and thrombocytopenia that did not improve with intravenous steroids or multiple transfusions of red cells and platelets.
Subsequent bone marrow biopsy showed severely depleted megakaryocytes and erythroid precursor cells with relative myeloid hyperplasia suggestive of amegakaryocytic thrombocytopenia and red cell aplasia.
He was started on oral cyclosporine but subsequently developed leukopenia and refused any further treatment or diagnostic procedures and left the hospital against medical advice.
AAMT, thus, may be a very early presentation of impending aplastic anemia, and treating physicians need to be aware of this entity.
American Psychological Association (APA)
Dahal, Sumit& Sharma, Eliza& Dahal, Suyash& Shrestha, Binav& Bhattarai, Bikash. 2018. Acquired Amegakaryocytic Thrombocytopenia and Pure Red Cell Aplasia in Thymoma. Case Reports in Hematology،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143872
Modern Language Association (MLA)
Dahal, Sumit…[et al.]. Acquired Amegakaryocytic Thrombocytopenia and Pure Red Cell Aplasia in Thymoma. Case Reports in Hematology No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1143872
American Medical Association (AMA)
Dahal, Sumit& Sharma, Eliza& Dahal, Suyash& Shrestha, Binav& Bhattarai, Bikash. Acquired Amegakaryocytic Thrombocytopenia and Pure Red Cell Aplasia in Thymoma. Case Reports in Hematology. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143872
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143872