Limited Exchange Transfusion Can Be Very Beneficial in Sickle Cell Anemia with Acute Chest Syndrome: A Case Report from Tanzania
Joint Authors
Makani, J.
Yonazi, Mbonea
Schuh, Anna
Chamba, Clara
Iddy, Hamisa
Tebuka, Erius
Tluway, Furahini
Osati, Elisha
Budodi, Neema
Meda, Collins
Luzzatto, Lucio
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-21
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Acute chest syndrome (ACS) is a life-threatening complication of sickle cell disease (SCD) with blood transfusion an integral part in its management.
Red cell exchange (RCE) transfusion is usually regarded as preferable to top-up transfusion, because it reduces the proportion of Hemoglobin (Hb) S while at the same time avoiding circulatory overload.
Despite its obvious benefits, RCE is underutilized, particularly in low-resource settings which may be due to scarcity of blood products and of expertise in carrying out exchange transfusion.
We report on a young woman with SCD with severe ACS who responded promptly and dramatically to a RCE of only 0.95 L (instead of the recommended 1.4 L) and had in the end an HbS level of 48% (instead of the recommended level below 30%).
Limited RCE resulted in significant clinical improvement.
We suggest that limited RCE may be of benefit than no RCE in SCD patients with ACS, particularly in settings where RCE is not available.
American Psychological Association (APA)
Chamba, Clara& Iddy, Hamisa& Tebuka, Erius& Tluway, Furahini& Osati, Elisha& Budodi, Neema…[et al.]. 2018. Limited Exchange Transfusion Can Be Very Beneficial in Sickle Cell Anemia with Acute Chest Syndrome: A Case Report from Tanzania. Case Reports in Hematology،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143878
Modern Language Association (MLA)
Chamba, Clara…[et al.]. Limited Exchange Transfusion Can Be Very Beneficial in Sickle Cell Anemia with Acute Chest Syndrome: A Case Report from Tanzania. Case Reports in Hematology No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1143878
American Medical Association (AMA)
Chamba, Clara& Iddy, Hamisa& Tebuka, Erius& Tluway, Furahini& Osati, Elisha& Budodi, Neema…[et al.]. Limited Exchange Transfusion Can Be Very Beneficial in Sickle Cell Anemia with Acute Chest Syndrome: A Case Report from Tanzania. Case Reports in Hematology. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143878
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143878