A Rare Case of ALK-Positive Large B-Cell Lymphoma with CD33 Expression
Joint Authors
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-11
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Anaplastic lymphoma kinase-positive large B-cell lymphoma (ALK+ LBCL) is a very rare and aggressive subtype of diffuse large B-cell lymphoma characterized by ALK rearrangement.
Immunophenotypically, the tumor cells are typically negative for common B-cell markers, T-cell markers, and CD30; however, they express markers of terminally differentiated B cells/plasma cells such as CD38, CD138, and MUM-1/IRF4.
The diagnosis of ALK+ LBCL can be challenging, and often a large panel of immunostains is required to exclude other hematopoietic and nonhematopoietic neoplasms.
To date, approximately 130–140 cases have been reported, but here we report the first known case of ALK+ LBCL with unusual CD33 expression.
American Psychological Association (APA)
Corean, Jessica& Li, K. David. 2018. A Rare Case of ALK-Positive Large B-Cell Lymphoma with CD33 Expression. Case Reports in Hematology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1143880
Modern Language Association (MLA)
Corean, Jessica& Li, K. David. A Rare Case of ALK-Positive Large B-Cell Lymphoma with CD33 Expression. Case Reports in Hematology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1143880
American Medical Association (AMA)
Corean, Jessica& Li, K. David. A Rare Case of ALK-Positive Large B-Cell Lymphoma with CD33 Expression. Case Reports in Hematology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1143880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143880
