Spontaneous Coronary Artery Dissection: A Rare Manifestation of Alport Syndrome
Joint Authors
Anuwatworn, Amornpol
Jonsson, Orvar
Sethi, Prince
Steffen, Kelly
Petrasko, Marian
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-14
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Alport syndrome (AS) is a genetic disorder due to inheritance of genetic mutations which lead to production of abnormal type IV collagen.
AS has been associated with renal, auditory, and ocular diseases due to the presence of abnormal alpha chains of type IV collagen in the glomerulus, cochlea, cornea, lens, and retina.
The resulting disorder includes hereditary nephritis, corneal opacities, anterior lenticonus, fleck retinopathy, temporal retinal thinning, and sensorineural deafness.
Aortic and aortic valve pathologies have been described as extrarenal manifestations of AS in multiple case reports.
One case report described intramural hematoma of the coronary artery.
We report the first case of true spontaneous coronary artery dissection (SCAD) with an intimal flap as a very rare manifestation of AS.
The patient is a 36-year-old female with history of AS with chronic kidney disease, hypertension, and obesity who presented to the emergency room with acute onset of substernal chest pain radiating to her neck and arms.
Troponin was elevated, and ECG showed transient 1 mm ST-segment elevation in the inferior leads.
Subsequent coronary angiography revealed localized dissection of the left circumflex artery.
Percutaneous coronary angioplasty was performed and her symptoms improved.
This case illustrates that SCAD may be a manifestation of AS patients with chest pain.
American Psychological Association (APA)
Anuwatworn, Amornpol& Sethi, Prince& Steffen, Kelly& Jonsson, Orvar& Petrasko, Marian. 2017. Spontaneous Coronary Artery Dissection: A Rare Manifestation of Alport Syndrome. Case Reports in Cardiology،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1143939
Modern Language Association (MLA)
Anuwatworn, Amornpol…[et al.]. Spontaneous Coronary Artery Dissection: A Rare Manifestation of Alport Syndrome. Case Reports in Cardiology No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1143939
American Medical Association (AMA)
Anuwatworn, Amornpol& Sethi, Prince& Steffen, Kelly& Jonsson, Orvar& Petrasko, Marian. Spontaneous Coronary Artery Dissection: A Rare Manifestation of Alport Syndrome. Case Reports in Cardiology. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1143939
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1143939