Plasmapheresis for Spur Cell Anemia in a Patient with Alcoholic Liver Cirrhosis
Joint Authors
Miki, Kenji
Maruki, Takashi
Imashuku, Shinsaku
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-21
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
Spur cell anemia (SCA) is a cause of hemolytic anemia in patients with alcoholic liver cirrhosis.
Because dyslipidemia is related to the development of spur cells, SCA was previously treated with plasmapheresis.
Case Report.
A 52-year-old Japanese man with SCA associated with alcoholic liver cirrhosis (Child–Pugh C) underwent two rounds of plasmapheresis.
Clinical features and serum lipid concentrations were compared before and after plasmapheresis.
Although indirect hyperbilirubinemia and SCA persisted after plasmapheresis, reticulocyte counts significantly decreased from 22.4% to 4.5%, and Hb levels improved without red cell transfusions.
Analysis of lipids showed that total and free cholesterol, HDL cholesterol, phospholipid, and apo-AI concentrations, all of which were reduced before plasmapheresis, had improved after treatment, while LDL cholesterol, lipoprotein (a), and apo-AII concentrations, which were also reduced before plasmapheresis, remained unchanged.
Conclusions.
Despite plasmapheresis partially ameliorating the degree of hemolysis, the persistence of SCA may have been linked with the lack of improvement in certain types of lipid metabolism.
American Psychological Association (APA)
Miki, Kenji& Maruki, Takashi& Imashuku, Shinsaku. 2018. Plasmapheresis for Spur Cell Anemia in a Patient with Alcoholic Liver Cirrhosis. Case Reports in Hematology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144129
Modern Language Association (MLA)
Miki, Kenji…[et al.]. Plasmapheresis for Spur Cell Anemia in a Patient with Alcoholic Liver Cirrhosis. Case Reports in Hematology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1144129
American Medical Association (AMA)
Miki, Kenji& Maruki, Takashi& Imashuku, Shinsaku. Plasmapheresis for Spur Cell Anemia in a Patient with Alcoholic Liver Cirrhosis. Case Reports in Hematology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144129
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144129