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Rupture of Hepatocellular Carcinoma after Transarterial Chemoembolization followed by Massive Gastric Bleeding
Joint Authors
Nishida, Kazuhiro
Funabiki, Tomohiro
Lefor, Alan T.
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-04
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Transarterial chemoembolization (TACE) is the first-line therapy for patient with unresectable hepatocellular carcinoma (HCC).
Although TACE is a generally safe procedure, major complications can be occurred.
We describe a patient with rupture of HCC after TACE followed by gastric bleeding.
Case Presentation.
An 81-year-old man presented with worsening epigastric pain.
He had been diagnosed with multiple HCC with nonalcoholic steatohepatitis and underwent TACE 19 days previously.
A contrast enhanced computed tomography (CT) scan of the abdomen showed rupture of an HCC.
He was treated nonoperatively and discharged on hospital day 18.
Five weeks after TACE, he was emergently admitted with massive hematochezia and shock.
A contrast enhanced CT scan demonstrated extrinsic gastric compression by an HCC lesion with extravasation of contrast into the stomach.
Emergent upper gastrointestinal endoscopy showed a bleeding gastric ulcer with extraluminal compression which was successfully controlled by hypertonic saline-epinephrine injection.
Due to tumor progression, he was discharged for palliative care and died six weeks after TACE.
Conclusion.
Rupture of HCC is a life-threatening complication after TACE with mortality rates up to 50%.
After treatment of a ruptured HCC, extragastric compression and bleeding can occur due to direct compression by a primary lesion or intraperitoneal dissemination.
American Psychological Association (APA)
Nishida, Kazuhiro& Lefor, Alan T.& Funabiki, Tomohiro. 2018. Rupture of Hepatocellular Carcinoma after Transarterial Chemoembolization followed by Massive Gastric Bleeding. Case Reports in Hepatology،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1144212
Modern Language Association (MLA)
Nishida, Kazuhiro…[et al.]. Rupture of Hepatocellular Carcinoma after Transarterial Chemoembolization followed by Massive Gastric Bleeding. Case Reports in Hepatology No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1144212
American Medical Association (AMA)
Nishida, Kazuhiro& Lefor, Alan T.& Funabiki, Tomohiro. Rupture of Hepatocellular Carcinoma after Transarterial Chemoembolization followed by Massive Gastric Bleeding. Case Reports in Hepatology. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1144212
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144212