Fatal Invasive Cryptococcal Infection in an HIV-Negative Elderly Patient with Decompensated Hepatic Cirrhosis
Joint Authors
Koba, Shigeru
Miki, Kenji
Ueda, Kazuki
Mori, Masahiro
Imashuku, Shinsaku
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Diagnosis of invasive cryptococcal infection in apparently nonimmunocompromised patients is difficult and often delayed.
Human immunodeficiency virus- (HIV-) negative patients with decompensated hepatic cirrhosis might be at high risk of cryptococcal infection.
We report here an 82-year-old Japanese female with end-stage hepatic failure and undergoing renal dialysis, hospitalized with septic shock-like symptoms.
The patient had had hepatitis B virus (HBV) infection in the past.
She survived only 4 days following admission.
During hospitalization, she was found to have pleural effusion and ascites.
Cryptococcus neoformans was obtained from blood culture but not from pleural effusion culture.
Consequently, the patient was diagnosed as having invasive cryptococcosis in association with HBV-related hepatic cirrhosis.
Unfortunately, the patient died prior to receiving antifungal agents.
Twelve Japanese cases of hepatic cirrhosis-related invasive cryptococcal infection, consisting of previously described and this case, were summarized for discussion of the clinical features and outcomes.
American Psychological Association (APA)
Koba, Shigeru& Ueda, Kazuki& Mori, Masahiro& Miki, Kenji& Imashuku, Shinsaku. 2018. Fatal Invasive Cryptococcal Infection in an HIV-Negative Elderly Patient with Decompensated Hepatic Cirrhosis. Case Reports in Hepatology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1144219
Modern Language Association (MLA)
Koba, Shigeru…[et al.]. Fatal Invasive Cryptococcal Infection in an HIV-Negative Elderly Patient with Decompensated Hepatic Cirrhosis. Case Reports in Hepatology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1144219
American Medical Association (AMA)
Koba, Shigeru& Ueda, Kazuki& Mori, Masahiro& Miki, Kenji& Imashuku, Shinsaku. Fatal Invasive Cryptococcal Infection in an HIV-Negative Elderly Patient with Decompensated Hepatic Cirrhosis. Case Reports in Hepatology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1144219
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144219