Epoetin Alfa: A Cause of Coronary Artery Thrombosis
Joint Authors
Siddiqui, Muhammad Umer
Galumyan, Yelena
Klein, James
Naeem, Zunaira
Schwarcz, Aron
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
Epoetin alfa is an erythrocyte-stimulating factor.
We here present a case of an anemic patient, who was given epogen before a coronary artery bypass (CABG) surgery and developed periprocedural myocardial infarction.
To our knowledge, there has been no previous case reported of epogen causing myocardial infarction.
Case Presentation.
66-year-old female presented with substernal chest pain.
EKG showed ST segment elevations in aVf and L-III.
Patient underwent left heart catheterization (LHC) and had triple vessel disease.
A bare metal stent was placed in RCA.
Patient continued to have symptoms after discharge and presented to the ED again with these complaints.
She underwent coronary artery bypass surgery (CABG).
Before the procedure, patient’s hemoglobin was 11.1 grams/deciliter and was given epogen to raise hemoglobin level.
Postoperative day (POD) #1 patient had ST elevations in inferior and anterolateral leads.
She was diagnosed with periprocedural myocardial infarction.
Patient underwent repeat LHC, which identified obstruction of saphenous vein graft (SVG).
Hypercoagulable workup was negative for any disease and the patient was diagnosed with epogen induced early graft occlusion.
Conclusion.
Epogen administration can cause myocardial infarction and coronary artery thrombosis.
We suggest that physicians use epogen very cautiously, especially in population who has underlying coronary artery disease.
American Psychological Association (APA)
Siddiqui, Muhammad Umer& Galumyan, Yelena& Klein, James& Naeem, Zunaira& Schwarcz, Aron. 2017. Epoetin Alfa: A Cause of Coronary Artery Thrombosis. Case Reports in Cardiology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1144273
Modern Language Association (MLA)
Siddiqui, Muhammad Umer…[et al.]. Epoetin Alfa: A Cause of Coronary Artery Thrombosis. Case Reports in Cardiology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1144273
American Medical Association (AMA)
Siddiqui, Muhammad Umer& Galumyan, Yelena& Klein, James& Naeem, Zunaira& Schwarcz, Aron. Epoetin Alfa: A Cause of Coronary Artery Thrombosis. Case Reports in Cardiology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1144273
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144273