Disseminated Necrotizing Leukoencephalopathy Complicating Septic Shock in an Immunocompetent Patient
Joint Authors
Reimão, Sofia
Santos, João Meneses
Victorino, Rui M. M.
Gaspar-da-Costa, Pedro
Braz, Sandra
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-24
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Disseminated necrotizing leukoencephalopathy (DNL) is characterized by multiple microscopic foci of white matter necrosis.
DNL was initially thought to be exclusively associated with immunosuppression conditions but it has been recently described in immunocompetent patients in septic shock.
A 90-year-old immunocompetent woman with no previous neurological impairment presented with septic shock and drowsiness that responded well to therapy with clinical improvement and a full neurological recovery.
Unexpectedly deterioration with progression to coma occurred.
Investigation excluded other causes and Magnetic Resonance Imaging (MRI) was consistent with the diagnosis of DNL showing bilateral multifocal white matter lesions with a nonvascular pattern with restricted diffusion.
Neurological impairment persisted with progression to death.
DNL is an unexpected diagnosis in an immunocompetent patient.
We compared the present case to those found in the literature of DNL complicating septic shock and discuss the antemortem diagnosis based on MRI findings.
American Psychological Association (APA)
Gaspar-da-Costa, Pedro& Reimão, Sofia& Braz, Sandra& Santos, João Meneses& Victorino, Rui M. M.. 2017. Disseminated Necrotizing Leukoencephalopathy Complicating Septic Shock in an Immunocompetent Patient. Case Reports in Critical Care،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1144325
Modern Language Association (MLA)
Gaspar-da-Costa, Pedro…[et al.]. Disseminated Necrotizing Leukoencephalopathy Complicating Septic Shock in an Immunocompetent Patient. Case Reports in Critical Care No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1144325
American Medical Association (AMA)
Gaspar-da-Costa, Pedro& Reimão, Sofia& Braz, Sandra& Santos, João Meneses& Victorino, Rui M. M.. Disseminated Necrotizing Leukoencephalopathy Complicating Septic Shock in an Immunocompetent Patient. Case Reports in Critical Care. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1144325
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144325