Successful Treatment of Severe Type B Lactic Acidosis in a Patient with HIVAIDS-Associated High-Grade NHL
Joint Authors
Carlan, S. J.
Madruga, Mario
Mejia, Marco
Perez, Ariel
Watson, Harold
Sanchez, Daniel
Parellada, Jorge
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-13
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Type B lactic acidosis is a rare metabolic complication sometimes associated with hematologic malignancies.
When present, this type of lactic acidosis is most commonly seen in patients with high-grade lymphomas or leukemias and is usually indicative of a dismal prognosis.
We report a case of a 27-year man with acquired immunodeficiency syndrome (AIDS) that presented with bilateral lower extremity swelling, an abdominal mass, and weight loss.
His lab values showed elevated anion gap with lactic acidosis and computed tomography (CT) of the abdomen showed a large soft-tissue mass arising from the left hepatic lobe.
Biopsy of the abdominal mass demonstrated a high-grade diffuse large B-cell lymphoma.
The patient’s lactic acidosis resolved after starting chemotherapy, and a complete response was evident on PET-CT after a third cycle of rituximab, etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin (EPOC-RR).
Care-givers should be aware of the implications of lactic acidosis associated with malignancy and the need for prompt diagnosis and treatment.
American Psychological Association (APA)
Mejia, Marco& Perez, Ariel& Watson, Harold& Sanchez, Daniel& Parellada, Jorge& Madruga, Mario…[et al.]. 2018. Successful Treatment of Severe Type B Lactic Acidosis in a Patient with HIVAIDS-Associated High-Grade NHL. Case Reports in Immunology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144335
Modern Language Association (MLA)
Mejia, Marco…[et al.]. Successful Treatment of Severe Type B Lactic Acidosis in a Patient with HIVAIDS-Associated High-Grade NHL. Case Reports in Immunology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1144335
American Medical Association (AMA)
Mejia, Marco& Perez, Ariel& Watson, Harold& Sanchez, Daniel& Parellada, Jorge& Madruga, Mario…[et al.]. Successful Treatment of Severe Type B Lactic Acidosis in a Patient with HIVAIDS-Associated High-Grade NHL. Case Reports in Immunology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144335
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144335