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An Evaluation of Rapidly Progressive Dementia Culminating in a Diagnosis of Creutzfeldt–Jakob Disease
Joint Authors
Kobewka, Daniel
Parmar, Parmvir
Cooper, Curtis L.
Source
Case Reports in Infectious Diseases
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-23
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Rapidly progressive dementia is a curious and elusive clinical description of a pattern of cognitive deficits that progresses faster than typical dementia syndromes.
The differential diagnosis and clinical workup for rapidly progressive dementia are quite extensive and involve searching for infectious, inflammatory, autoimmune, neoplastic, metabolic, and neurodegenerative causes.
We present the case of a previously highly functional 76-year-old individual who presented with a 6-month history of rapidly progressive dementia.
His most prominent symptoms were cognitive impairment, aphasia, visual hallucinations, and ataxia.
Following an extensive battery of tests in hospital, the differential diagnosis remained probable CJD versus autoimmune encephalitis.
He clinically deteriorated and progressed to akinetic mutism and myoclonus.
He passed away 8 weeks after his initial presentation to hospital, and an autopsy confirmed a diagnosis of sporadic CJD.
We use this illustrative case as a framework to discuss the clinical and diagnostic considerations in the workup for rapidly progressive dementia.
We also discuss CJD and autoimmune encephalitis, the two main diagnostic possibilities in our patient, in more detail.
American Psychological Association (APA)
Parmar, Parmvir& Cooper, Curtis L.& Kobewka, Daniel. 2018. An Evaluation of Rapidly Progressive Dementia Culminating in a Diagnosis of Creutzfeldt–Jakob Disease. Case Reports in Infectious Diseases،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144421
Modern Language Association (MLA)
Parmar, Parmvir…[et al.]. An Evaluation of Rapidly Progressive Dementia Culminating in a Diagnosis of Creutzfeldt–Jakob Disease. Case Reports in Infectious Diseases No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1144421
American Medical Association (AMA)
Parmar, Parmvir& Cooper, Curtis L.& Kobewka, Daniel. An Evaluation of Rapidly Progressive Dementia Culminating in a Diagnosis of Creutzfeldt–Jakob Disease. Case Reports in Infectious Diseases. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1144421
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144421