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Listeria monocytogenes Brain Abscess: Controversial Issues for the Treatment—Two Cases and Literature Review
Joint Authors
Saraca, L. M.
Priante, G.
Francisci, D.
Tiri, Beatrice
Martella, Lucia Assunta
Cappanera, Stefano
Source
Case Reports in Infectious Diseases
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Listeria monocytogenes (LM) is an opportunistic pathogen, and the most common central nervous system manifestation is meningitis while listerial brain abscesses are rare.
We describe 2 cases of brain abscess due to LM and a literature review.
Only 73 cases were reported in the literature from 1968 to 2017.
The mean age was 51.9, and the mortality rate was 27.3%.
In 19% of cases, no risk factors for neurolisteriosis were identified.
Blood cultures were positive in 79.5% while CSF or brain abscess biopsy material was positive in 50.8%.
In 40% was started a monotherapy regimen while in 60% a combination therapy without substantial differences in mortality.
Fifty-two percent underwent neurosurgery while 45.3% has been treated only with medical therapy.
The mortality rates were, respectively, 13% and 38.2%.
Only 25% of patients who were treated for ≤6 weeks underwent neurosurgery, while 80% of those who were treated for ≥8 weeks were operated.
The mortality rates were, respectively, 12.5% and 0%, suggesting that a combined approach of surgery and prolonged medical therapy would have an impact on mortality.
We believe that it is essential to carry out this review as brain abscesses are rare, and there are no definitive indications on the optimal management, type, and duration of therapy.
American Psychological Association (APA)
Tiri, Beatrice& Priante, G.& Saraca, L. M.& Martella, Lucia Assunta& Cappanera, Stefano& Francisci, D.. 2018. Listeria monocytogenes Brain Abscess: Controversial Issues for the Treatment—Two Cases and Literature Review. Case Reports in Infectious Diseases،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1144608
Modern Language Association (MLA)
Tiri, Beatrice…[et al.]. Listeria monocytogenes Brain Abscess: Controversial Issues for the Treatment—Two Cases and Literature Review. Case Reports in Infectious Diseases No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1144608
American Medical Association (AMA)
Tiri, Beatrice& Priante, G.& Saraca, L. M.& Martella, Lucia Assunta& Cappanera, Stefano& Francisci, D.. Listeria monocytogenes Brain Abscess: Controversial Issues for the Treatment—Two Cases and Literature Review. Case Reports in Infectious Diseases. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1144608
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1144608